PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28624441-0	2017	Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway.	Sunitinib	60-69	heat shock protein 90 alpha family class A member 1	Homo sapiens	0-5	
35209964-8	2022	In the supernatant of FLC-4 cells with sunitinib, the heat shock protein (HSP) 90 was significantly increased.	Sunitinib	39-48	heat shock protein 90 alpha family class A member 1	Homo sapiens	54-81	
28624441-3	2017	Here, we examined the effect of geldanamycin, an inhibitor of heat shock protein (Hsp) 90, on sunitinib-induced cytotoxicity in cardiomyocytes.	Sunitinib	94-103	heat shock protein 90 alpha family class A member 1	Homo sapiens	62-89	
28624441-10	2017	Thus, the further investigation of combination or sequential treatment with an Hsp90 inhibitor and sunitinib is warranted as a potential strategy of attenuating the cardiotoxicity associated with sunitinib administration in the clinical setting.	Sunitinib	196-205	heat shock protein 90 alpha family class A member 1	Homo sapiens	79-84	
19467916-5	2009	We discuss how the cross-talk between major downstream signaling pathways, such as PI3K/PTEN/Akt/mTOR, RAS/Raf/MEK/ERK, and Jak/STAT, can be exploited for therapeutic purposes by targeting key signaling molecules with selective inhibitors, such as mTOR inhibitors, HSP90 inhibitors, or farnesyltransferase inhibitors, and identifying those agents with the ability to positively combine with inhibitors of FLT3, such as PKC412 and sunitinib.	Sunitinib	430-439	heat shock protein 90 alpha family class A member 1	Homo sapiens	265-270