PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29551130-6 2018 The first TK to be targeted, Bcr-Abl, led to the generation of several drugs including imatinib, dasatinib, and sunitinib that provided a rich understanding of this phenomenon. Sunitinib 112-121 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 29-36 25130811-8 2014 The mRNA expression of C-MYC, hTERT and BCR-ABL was reduced significantly by SU11248 in a time-dependent manner (P < 0.05). Sunitinib 77-84 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 40-47 25130811-10 2014 It is concluded that SU11248 can inhibit the growth of K562 cells efficiently through inducing apoptosis, its mechanism may be closely relate with the expression down-regulation of C-MYC, hTERT, BCR-ABL and the inhibition of Akt phosphorylation. Sunitinib 21-28 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 195-202