PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32760216-0 2020 LncRNA HOTAIR induces sunitinib resistance in renal cancer by acting as a competing endogenous RNA to regulate autophagy of renal cells. Sunitinib 22-31 HOX transcript antisense RNA (non-protein coding) Mus musculus 7-13 32760216-3 2020 This study was assigned to probe the effect and mechanism of HOTAIR on sunitinib resistance of RC. Sunitinib 71-80 HOX transcript antisense RNA (non-protein coding) Mus musculus 61-67 32760216-11 2020 The role of HOTAIR knockdown in sunitinib resistance was verified in nude mice. Sunitinib 32-41 HOX transcript antisense RNA (non-protein coding) Mus musculus 12-18 32760216-12 2020 Results: HOTAIR expression in sunitinib-resistant cells is higher than that in parental cells. Sunitinib 30-39 HOX transcript antisense RNA (non-protein coding) Mus musculus 9-15 32760216-13 2020 Knockdown of HOTAIR in sunitinib-resistant cells lead to refrained sunitinib resistance and cell autophagy both in vivo and in vitro. Sunitinib 23-32 HOX transcript antisense RNA (non-protein coding) Mus musculus 13-19 32760216-13 2020 Knockdown of HOTAIR in sunitinib-resistant cells lead to refrained sunitinib resistance and cell autophagy both in vivo and in vitro. Sunitinib 67-76 HOX transcript antisense RNA (non-protein coding) Mus musculus 13-19 32760216-17 2020 Conclusion: HOTAIR negatively targets miR-17-5p to activate Beclin1-mediated cell autophagy, thereby enhancing sunitinib resistance in RC cells. Sunitinib 111-120 HOX transcript antisense RNA (non-protein coding) Mus musculus 12-18