PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30393183-4 2018 These micellar formulations exhibited sustained release of sunitinib for around 50% at 24 h and protected siAlox15 from serum degradation for at least 10 h. Further, both sunitinib and siAlox15 inhibited human peripheral blood mononuclear cell (PBMC) proliferation and activation by downregulating the phosphorylation of Akt, platelet-derived growth factor receptor (PDGFR) at protein levels and Alox15 in mRNA levels, respectively. Sunitinib 171-180 arachidonate 15-lipoxygenase Homo sapiens 108-114