PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29727629-11 2018 The appearance of microalbuminuria and reduced nephrin expression was prevented by losartan at week 12. Losartan 83-91 NPHS1 adhesion molecule, nephrin Homo sapiens 47-54 28353407-5 2017 NPHS1 variation rs3814995 was associated with losartan effect in LIFE. Losartan 46-54 NPHS1 adhesion molecule, nephrin Homo sapiens 0-5 25264225-1 2016 OBJECTIVE: To investigate the function of nephrin in podocytes and its relation to proteinuria in kidney diseases, and to study more clearly theoretical basis for the molecular mechanism of losartan anti-proteinuria and the special beneficial effects of losartan on podocyte injury. Losartan 254-262 NPHS1 adhesion molecule, nephrin Homo sapiens 42-49 25264225-5 2016 Apoptotic podocytes may related to the decrease of nephrin mRNA and protein expressions, losartan reduced the apoptosis and proteinuria by declining nephrin mRNA and protein expressions. Losartan 89-97 NPHS1 adhesion molecule, nephrin Homo sapiens 149-156 25264225-6 2016 CONCLUSION: Ang II induced podocyte injury caused abnormal expression and distribution of nephrin in podocytes, losartan maybe maintain the stability of nephrin expression and the integrity of hole diaphragm (SD) structure and function by blocking the signal path, playing a important role in protection mechanisms of anti-proteinuria. Losartan 112-120 NPHS1 adhesion molecule, nephrin Homo sapiens 90-97 25264225-6 2016 CONCLUSION: Ang II induced podocyte injury caused abnormal expression and distribution of nephrin in podocytes, losartan maybe maintain the stability of nephrin expression and the integrity of hole diaphragm (SD) structure and function by blocking the signal path, playing a important role in protection mechanisms of anti-proteinuria. Losartan 112-120 NPHS1 adhesion molecule, nephrin Homo sapiens 153-160 25622599-9 2015 Replication analyses of GENRES results provided suggestive evidence for a missense variant (rs3814995) in the NPHS1 (nephrin) gene influencing losartan response, and for 2 variants influencing hydrochlorothiazide response, located within or close to the ALDH1A3 (rs3825926) and CLIC5 (rs321329) genes. Losartan 143-151 NPHS1 adhesion molecule, nephrin Homo sapiens 110-115 25622599-9 2015 Replication analyses of GENRES results provided suggestive evidence for a missense variant (rs3814995) in the NPHS1 (nephrin) gene influencing losartan response, and for 2 variants influencing hydrochlorothiazide response, located within or close to the ALDH1A3 (rs3825926) and CLIC5 (rs321329) genes. Losartan 143-151 NPHS1 adhesion molecule, nephrin Homo sapiens 117-124