PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28844872-0	2017	Losartan protects against cerebral ischemia/reperfusion-induced apoptosis through beta-arrestin1-mediated phosphorylation of Akt.	Losartan	0-8	arrestin, beta 1	Rattus norvegicus	82-96	
28844872-8	2017	Furthermore, pretreatment with losartan significantly increased the protein level of beta-arrestin1 and silence of beta-arrestin1 by siRNA partly attenuated losartan-induced anti-apoptotic effect and the phosphorylation of Akt.	Losartan	31-39	arrestin, beta 1	Rattus norvegicus	85-99	
28844872-8	2017	Furthermore, pretreatment with losartan significantly increased the protein level of beta-arrestin1 and silence of beta-arrestin1 by siRNA partly attenuated losartan-induced anti-apoptotic effect and the phosphorylation of Akt.	Losartan	31-39	arrestin, beta 1	Rattus norvegicus	115-129	
28844872-8	2017	Furthermore, pretreatment with losartan significantly increased the protein level of beta-arrestin1 and silence of beta-arrestin1 by siRNA partly attenuated losartan-induced anti-apoptotic effect and the phosphorylation of Akt.	Losartan	157-165	arrestin, beta 1	Rattus norvegicus	85-99	
28844872-8	2017	Furthermore, pretreatment with losartan significantly increased the protein level of beta-arrestin1 and silence of beta-arrestin1 by siRNA partly attenuated losartan-induced anti-apoptotic effect and the phosphorylation of Akt.	Losartan	157-165	arrestin, beta 1	Rattus norvegicus	115-129	
28844872-9	2017	These results suggested that beta-arrestin1 modulated the activation of Akt in losartan-induced anti-apoptotic effect in cerebral I/R.	Losartan	79-87	arrestin, beta 1	Rattus norvegicus	29-43	
15734891-7	2005	Treatment of AVS animals with imidapril (1 mg.kg(-1).day(-1)) or losartan (20 mg.kg(-1).day(-1)) retarded the progression of heart failure; partially prevented changes in beta1-ARs, GRKs, and beta-arrestin-1 in the failing myocardium; and attenuated the increase in positive inotropic effect of isoproterenol.	Losartan	65-73	arrestin, beta 1	Rattus norvegicus	192-207