PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34094856-11 2021 Losartan treatment or PPARgamma activation contributes to reduced levels of IL-6, IL-1beta, TNF-alpha, and COX-2, expression of TGF-beta1, MMP-13, ADAMTS-4, ADAMTS-5, HtrA1, and iNOS, along with reduced Smad2 and Smad3 phosphorylation, but elevated PPARgamma and Collagen II expression in vivo and in vitro. Losartan 0-8 nitric oxide synthase 2, inducible Mus musculus 178-182