PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22846543-0	2012	Wogonin induces apoptosis by activating the AMPK and p53 signaling pathways in human glioblastoma cells.	wogonin	0-7	tumor protein p53	Homo sapiens	53-56	
35178099-11	2022	The experimental results showed that baicalein and wogonin could inhibit proliferation and induce apoptosis of NPC cells and downregulate the expression of PI3K, AKT, and p53, the key proteins of the PI3K/AKT and p53 signaling pathway in CNE2 cells.	wogonin	51-58	tumor protein p53	Homo sapiens	171-174	
35178099-11	2022	The experimental results showed that baicalein and wogonin could inhibit proliferation and induce apoptosis of NPC cells and downregulate the expression of PI3K, AKT, and p53, the key proteins of the PI3K/AKT and p53 signaling pathway in CNE2 cells.	wogonin	51-58	tumor protein p53	Homo sapiens	213-216	
35178099-12	2022	Conclusion: Baicalein and wogonin, the main active ingredients of S. barbata, inhibited the proliferation and induced apoptosis of NPC cells through the PI3K/AKT and p53 signaling pathways.	wogonin	26-33	tumor protein p53	Homo sapiens	166-169	
31677863-0	2019	Corrigendum to "Selective anti-tumor activity of wogonin targeting the Warburg effect through stablizing p53" [Pharmacol.	wogonin	49-56	tumor protein p53	Homo sapiens	105-108	
22182776-5	2012	Wogonin-induced apoptosis was accompanied by a significant decrease of the Bcl-2 and survivin and increase of Bax and p53.	wogonin	0-7	tumor protein p53	Homo sapiens	118-121	
19935879-7	2009	Collectively, our data suggested that wogonin induced G1 phase arrest in HeLa cells by modulating several key G1 regulatory proteins, such as Cdk4 and cyclin D1, as well as up-regulation of a p53-mediated p21Cip1 expression.	wogonin	38-45	tumor protein p53	Homo sapiens	192-195	
18377871-8	2008	Further characterization of the transcriptional response to wogonin in HCT116 human colon cancer cells demonstrated that PUMA induction was p53-dependent; deficiency in either p53 or PUMA significantly protected HCT116 cells against wogonin-induced apoptosis.	wogonin	60-67	tumor protein p53	Homo sapiens	176-179	
32723300-1	2020	BACKGROUND: Wogonin, a natural flavonoid-like chemical compound, exhibits anti-inflammatory, antitumor, antiviral, neuroprotective, and anxiolytic effects by modulating a variety of cellular signaling pathways including PI3K-Akt, p53, nuclear factor kappaB (NF-kappaB), mitogen-activated protein kinase (MAPK) pathways.	wogonin	12-19	tumor protein p53	Homo sapiens	230-233