PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11502881-10 2001 Taken together, our results demonstrate that Wog inhibits MCP-1 induction in ECs; this inhibition is mediated by reducing AP-1 transcriptional activity via the attenuation of ERK1/2 and JNK signal transduction pathways. wogonin 45-48 C-C motif chemokine ligand 2 Homo sapiens 58-63 35593365-12 2022 The results indicated that quercetin and wogonin had better affinity with CXCL8, CCL2 or IL1B. wogonin 41-48 C-C motif chemokine ligand 2 Homo sapiens 81-85 35593365-14 2022 The expression CXCL8, CCL2 or IL1B were down-regulated after quercetin or wogonin treating, compared with LPS-induced A549 cells (P < 0.01). wogonin 74-81 C-C motif chemokine ligand 2 Homo sapiens 22-26 33520015-11 2020 Finally, 6 key proteins of TNF, IL-10, IL-2, IL-6, STAT1 and CCL2 were selected and successfully docked with 4 active ingredients of quercetin, luteolin, wogonin and kaempferol. wogonin 154-161 C-C motif chemokine ligand 2 Homo sapiens 61-65 35135448-9 2022 Molecular docking and dynamics simulations were performed to study the interaction between selected target genes (Chemokine ligand 2 (CCL2) and matrix metalloproteinase 1 (MMP1)) and active ingredients (quercetin and wogonin) of Ermiao San. wogonin 217-224 C-C motif chemokine ligand 2 Homo sapiens 134-138 35135448-11 2022 CCL2 and MMP1 were identified and verified to be the targets of both quercetin and wogonin, the two active ingredients of Ermiao San, by molecular docking and molecular dynamics. wogonin 83-90 C-C motif chemokine ligand 2 Homo sapiens 0-4