PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33009882-6	2021	Moreover, UA had no effects on HuR expression, but promoted the cytoplasm-nucleus translocation of HuR protein, decreased MDR1 mRNA stability and thus reduced MDR1 expression.	ursolic acid	10-12	ATP binding cassette subfamily B member 1	Homo sapiens	122-126	
28288941-6	2017	Carnosic acid, carnosol, and ursolic acid, but not rosmarinic acid, increased hPXR target gene expression, as shown by an increase in CYP3A4, UGT1A3, and ABCB1 mRNA expression in LS180 human colon adenocarcinoma cells.	ursolic acid	29-41	ATP binding cassette subfamily B member 1	Homo sapiens	154-159	
27604859-0	2016	Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1alpha.	ursolic acid	0-12	ATP binding cassette subfamily B member 1	Homo sapiens	87-91	
27604859-12	2016	CONCLUSIONS: Ursolic acid exerted chemosensitizing effects in colon cancer cells under hypoxia by inhibiting HIF-1alpha accumulation and the subsequent expression of the MDR1 and VEGF.	ursolic acid	13-25	ATP binding cassette subfamily B member 1	Homo sapiens	170-174	
33009882-6	2021	Moreover, UA had no effects on HuR expression, but promoted the cytoplasm-nucleus translocation of HuR protein, decreased MDR1 mRNA stability and thus reduced MDR1 expression.	ursolic acid	10-12	ATP binding cassette subfamily B member 1	Homo sapiens	159-163	
30572191-7	2019	Taken together, inhibition of P-gp function and disruption of the metabolism of energy and related amino acids could be the key mechanisms by which UA could reverse the MDR.	ursolic acid	148-150	ATP binding cassette subfamily B member 1	Homo sapiens	30-34	
30572191-5	2019	The synergistic effects were yielded by the combination of UA and Dox based on the investigation of the intracellular accumulation, the P-glycoprotein (P-gp) mediated transport, the energy metabolism including glycolysis, tricarboxylic acid (TCA) cycle, and glutamine metabolism as well as related amino acid metabolism.	ursolic acid	59-61	ATP binding cassette subfamily B member 1	Homo sapiens	136-150