PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27698874-9	2016	The results of the present study indicate that the anticancer effect of ursolic acid activates cell apoptosis through ROCK/PTEN mediated mitochondrial translocation of cofilin-1 in prostate cancer.	ursolic acid	72-84	cofilin 1	Homo sapiens	168-177	
29435058-0	2018	Ursolic acid activates the apoptosis of prostate cancer via ROCK/PTEN mediated mitochondrial translocation of cofilin-1.	ursolic acid	0-12	cofilin 1	Homo sapiens	110-119	
29435058-8	2018	In conclusion, these findings demonstrated that ursolic acid activates the apoptosis of prostate cancer via ROCK/PTEN mediated cofilin-1/cytochrome c which mediated caspase-3/9 activities.	ursolic acid	48-60	cofilin 1	Homo sapiens	127-136	
27698874-0	2016	Anti-cancer effect of ursolic acid activates apoptosis through ROCK/PTEN mediated mitochondrial translocation of cofilin-1 in prostate cancer.	ursolic acid	22-34	cofilin 1	Homo sapiens	113-122	
27698874-8	2016	Ursolic acid significantly suppressed the ROCK/PTEN signaling pathway and inhibited cofilin-1 protein expression in DU145 cells.	ursolic acid	0-12	cofilin 1	Homo sapiens	84-93	
24197982-0	2014	Mitochondrial translocation of cofilin-1 promotes apoptosis of gastric cancer BGC-823 cells induced by ursolic acid.	ursolic acid	103-115	cofilin 1	Homo sapiens	31-40	
24197982-4	2014	In our present study, we found in apoptotic gastric cancer BGC-823 cells induced by ursolic acid that a translocation of cofilin-1 protein from the cytoplasm to the mitochondria promoted the release of cytochrome c from the mitochondria to the cytoplasm, thereby activating the caspase cascade and finally inducing gastric cancer cell apoptosis.	ursolic acid	84-96	cofilin 1	Homo sapiens	121-130	
25520072-0	2014	Ursolic acid promotes apoptosis of SGC-7901 gastric cancer cells through ROCK/PTEN mediated mitochondrial translocation of cofilin-1.	ursolic acid	0-12	cofilin 1	Homo sapiens	123-132	
25520072-5	2014	Further mechanistic studies revealed that the ROCK1/PTEN signaling pathway plays a critical role in UA-mediated mitochondrial translocation of cofilin-1 and apoptosis.	ursolic acid	100-102	cofilin 1	Homo sapiens	143-152	
25520072-6	2014	These findings imply that induction of apoptosis by ursolic acid stems primarily from the activation of ROCK1 and PTEN, resulting in the translocation of cofilin-1 from cytoplasm to mitochondria, release of cytochrome c, activation of caspase-3 and caspase-9, and finally inducing apoptosis of gastric cancer SGC-7901 cells.	ursolic acid	52-64	cofilin 1	Homo sapiens	154-163