PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31061311-4 2019 Additional experiments show that UA inhibits cell migration and epithelial-mesenchymal transition (EMT), including E-cadherin, Vimentin, Integrin, Twist, and Zeb1 biomakers. ursolic acid 33-35 zinc finger E-box binding homeobox 1 Homo sapiens 158-162 33493421-0 2021 Ursolic Acid Enhances Cytotoxicity of Doxorubicin-Resistant Triple-Negative Breast Cancer Cells via ZEB1-AS1/miR-186-5p/ABCC1 Axis. ursolic acid 0-12 zinc finger E-box binding homeobox 1 Homo sapiens 100-104 33493421-11 2021 Importantly, UA treatment impaired the malignant phenotypes of DOX-resistant MDA-MB-468 and MDA-MB-436 cells through ZEB1-AS1/ABCC1 axis. ursolic acid 13-15 zinc finger E-box binding homeobox 1 Homo sapiens 117-121 31452805-0 2019 Ursolic acid suppresses the invasive potential of colorectal cancer cells by regulating the TGF-beta1/ZEB1/miR-200c signaling pathway. ursolic acid 0-12 zinc finger E-box binding homeobox 1 Homo sapiens 102-106 31452805-8 2019 Furthermore, following UA treatment, several crucial mediators of the TGF-beta1 signaling pathway, including TGF-beta1, phosphorylated (p)-Smad2/3, p-focal adhesion kinase and ZEB1, were significantly downregulated in the HCT116 and HCT-8 cell lines compared with the control group. ursolic acid 23-25 zinc finger E-box binding homeobox 1 Homo sapiens 176-180 31452805-11 2019 Collectively, the present study suggested that inhibition of CRC cell invasion by UA occurred via regulation of the TGF-beta1/ZEB1/miR-200c signaling network, which may be one of the mechanisms by which UA appears to be an effective therapeutic agent against colon cancer. ursolic acid 82-84 zinc finger E-box binding homeobox 1 Homo sapiens 126-130 31452805-11 2019 Collectively, the present study suggested that inhibition of CRC cell invasion by UA occurred via regulation of the TGF-beta1/ZEB1/miR-200c signaling network, which may be one of the mechanisms by which UA appears to be an effective therapeutic agent against colon cancer. ursolic acid 203-205 zinc finger E-box binding homeobox 1 Homo sapiens 126-130