PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25499383-8 2014 In the overall comparison, reduction of both SBP and DBP with eplerenone was greater than other antihypertensive agents (WMD for SBP -1.50 mm Hg, p < 0.0001; WMD for DBP -0.54 mm Hg, p < 0.00001); this was essentially driven by a greater anti-hypertensive action vs enalapril and losartan for SBP and vs losartan for DBP. Eplerenone 62-72 selenium binding protein 1 Homo sapiens 129-132 30985644-7 2019 Systolic/diastolic blood pressure (SBP/DBP) were reduced from 153.9 +- 12.6/84.6 +- 11.8 to 129.8 +- 14.2/73.7 +- 12.2 mm Hg by eplerenone therapy and from 152.2 +- 12.5/85.2 +- 10.9 to 133.8 +- 12.6/76.1 +- 8.6 mm Hg by trichlormethiazide therapy (all; P < .001). Eplerenone 128-138 selenium binding protein 1 Homo sapiens 35-38 25499383-7 2014 Compared to placebo, eplerenone significantly reduced either SBP [WMD -8.07, 95% CI -8.17 to -7.96 mm Hg, p < 0.00001] and DBP [WMD -4.08, -4.15 to -4.01 mm Hg, p < 0.00001]. Eplerenone 21-31 selenium binding protein 1 Homo sapiens 61-64 25499383-4 2014 Randomized studies comparing eplerenone with placebo or other antihypertensive drugs for net reduction of systolic and diastolic blood pressures (SBP; DBP) from baseline and for incidence of adverse events were considered. Eplerenone 29-39 selenium binding protein 1 Homo sapiens 146-149 23314743-7 2013 RESULTS: Eplerenone significantly decreased more 24-h ambulatory SBP on day 66 than LCI699 on day 29 and the difference between the two treatment was -5.34 [95% confidence interval (CI) -10.30; -0.38)] mmHg (P = 0.027). Eplerenone 9-19 selenium binding protein 1 Homo sapiens 65-68