PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31373631-4	2019	AngII activation of MR was blocked by the MR antagonist spironolactone or eplerenone and the protein kinase C-delta (PKCdelta) inhibitor rottlerin, implicating both in the mechanism.	Eplerenone	74-84	angiotensinogen	Homo sapiens	0-5	
23856493-8	2013	Intracerebroventricular infusion of FAD286 or eplerenone did not affect the initial pressor responses but similarly prevented 60% to 70% of the chronic pressor responses to intracerebroventricular infusion of Ang II.	Eplerenone	46-56	angiotensinogen	Homo sapiens	209-215	
18585409-0	2008	Eplerenone inhibits the intracrine and extracellular actions of angiotensin II on the inward calcium current in the failing heart.	Eplerenone	0-10	angiotensinogen	Homo sapiens	64-78	
18585409-4	2008	The results indicated that eplerenone suppressed the intracrine action of Ang II (10(-)(8) M) on peak I(Ca) density.	Eplerenone	27-37	angiotensinogen	Homo sapiens	74-80	
18585409-6	2008	The extracellular administration of Ang II (10(-)(8) M) incremented the peak I(Ca) density by only 20+/-8% (n=30) compared with 38+/-4% (n=35) (P<0.05) obtained in age-matched cardiomyopathic hamsters not exposed to eplerenone.	Eplerenone	219-229	angiotensinogen	Homo sapiens	36-42	
18585409-8	2008	IN CONCLUSION: a) eplerenone inhibits the intracrine action of Ang II on inward calcium current and reduces drastically the effect of extracellular Ang II on I(Ca); b) aldosterone is able to revert the effect of eplerenone; c) the mineralocorticoid receptor is an essential component of the intracrine renin angiotensin aldosterone system.	Eplerenone	18-28	angiotensinogen	Homo sapiens	63-69	
18585409-8	2008	IN CONCLUSION: a) eplerenone inhibits the intracrine action of Ang II on inward calcium current and reduces drastically the effect of extracellular Ang II on I(Ca); b) aldosterone is able to revert the effect of eplerenone; c) the mineralocorticoid receptor is an essential component of the intracrine renin angiotensin aldosterone system.	Eplerenone	212-222	angiotensinogen	Homo sapiens	63-69