PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35506380-10 2022 AS-/- mice exhibited transient Na+ wasting under low-salt diet, but administration of the MR antagonist eplerenone to AS-/- mice led to hyperkalemia and decreased body weight with higher Na+ excretion, mimicking the phenotype of MR-/- mice. Eplerenone 104-114 cytochrome P450, family 11, subfamily b, polypeptide 2 Mus musculus 0-2 35506380-10 2022 AS-/- mice exhibited transient Na+ wasting under low-salt diet, but administration of the MR antagonist eplerenone to AS-/- mice led to hyperkalemia and decreased body weight with higher Na+ excretion, mimicking the phenotype of MR-/- mice. Eplerenone 104-114 cytochrome P450, family 11, subfamily b, polypeptide 2 Mus musculus 118-120 23232789-7 2012 Messenger RNA expression of the mineralocorticoid receptor and aldosterone synthase were also reduced by eplerenone to a greater extent in early ATS, and these might increase the sensitivity of macrophages to mineralocorticoid blockade in early ATS. Eplerenone 105-115 cytochrome P450, family 11, subfamily b, polypeptide 2 Mus musculus 63-83 19255254-7 2009 Eplerenone (an aldosterone antagonist) abolished all of the effects of aldosterone-synthase overexpression but had no effect in Wt-D mice. Eplerenone 0-10 cytochrome P450, family 11, subfamily b, polypeptide 2 Mus musculus 71-91