PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19464421-8 2009 Eplerenone, after covariate adjustment, significantly decreased MMP-2 and increased MMP-9 over 24 weeks relative to placebo. Eplerenone 0-10 matrix metallopeptidase 9 Homo sapiens 84-89 22742718-0 2012 Usefulness of matrix metalloproteinase-9 plasma levels to identify patients with preserved left ventricular systolic function after acute myocardial infarction who could benefit from eplerenone. Eplerenone 183-193 matrix metallopeptidase 9 Homo sapiens 14-40 22742718-7 2012 However, a significant beneficial eplerenone effect on outcome was observed in patients with low baseline levels of MMP-9 (event-free survival for eplerenone vs noneplerenone arm 65% vs 35%, p = 0.005). Eplerenone 34-44 matrix metallopeptidase 9 Homo sapiens 116-121 22742718-7 2012 However, a significant beneficial eplerenone effect on outcome was observed in patients with low baseline levels of MMP-9 (event-free survival for eplerenone vs noneplerenone arm 65% vs 35%, p = 0.005). Eplerenone 147-157 matrix metallopeptidase 9 Homo sapiens 116-121 22742718-9 2012 In conclusion, in patients after AMI with preserved LV systolic function, low baseline levels of MMP-9 identify a subgroup of patients in whom eplerenone use is associated with a survival benefit. Eplerenone 143-153 matrix metallopeptidase 9 Homo sapiens 97-102