PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21951301-10 2012 COX-2 mRNA and NF-kappaB protein were significantly elevated in the peripheral nerves of diabetic rats compared with control rats, and treatment with eplerenone or candesartan reduced these changes in gene expression (p < 0.05). Eplerenone 150-160 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 0-5 16627578-5 2006 The inflammatory markers ED-1, osteopontin, and cyclooxygenase-2 remained significantly elevated despite the withdrawal of DOC (DOC404), whereas eplerenone restored cyclooxygenase-2 expression (but not that of ED-1 or osteopontin) to control levels. Eplerenone 145-155 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 165-181