PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34351585-6 2021 RESULTS: While blood pressure and kidney function were similar in the placebo and eplerenone treatment group during the study period, distinct differences in RAAS regulation occurred: eplerenone treatment resulted in an increase in plasma renin activity, Ang I and aldosterone concentrations, indicating global RAAS activation. Eplerenone 82-92 angiogenin Homo sapiens 255-258 34351585-6 2021 RESULTS: While blood pressure and kidney function were similar in the placebo and eplerenone treatment group during the study period, distinct differences in RAAS regulation occurred: eplerenone treatment resulted in an increase in plasma renin activity, Ang I and aldosterone concentrations, indicating global RAAS activation. Eplerenone 184-194 angiogenin Homo sapiens 255-258 18585409-8 2008 IN CONCLUSION: a) eplerenone inhibits the intracrine action of Ang II on inward calcium current and reduces drastically the effect of extracellular Ang II on I(Ca); b) aldosterone is able to revert the effect of eplerenone; c) the mineralocorticoid receptor is an essential component of the intracrine renin angiotensin aldosterone system. Eplerenone 18-28 angiogenin Homo sapiens 63-66