PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8713998-5 1995 We have measured the effect of oxytocin on the formation of inositol phosphates (InsPs) in cultured human myometrial cells labelled with [3H] inositol and on changes in intracellular free Ca2+ concentration ([Ca2+i]) in single cells using a dynamic calcium imaging system. Inositol Phosphates 60-79 oxytocin/neurophysin I prepropeptide Homo sapiens 31-39 9548257-4 1998 P4 inhibits oxytocin binding to OTR-containing membranes in vitro, binds with high affinity to recombinant rat OTR expressed in CHO cells, and suppresses oxytocin-induced inositol phosphate production and calcium mobilization. Inositol Phosphates 171-189 oxytocin/neurophysin I prepropeptide Homo sapiens 154-162 7475979-5 1995 The OT receptor in 293 cells, like in human myometrium, is also coupled to the inositol phosphate pathway. Inositol Phosphates 79-97 oxytocin/neurophysin I prepropeptide Homo sapiens 4-6 7475979-6 1995 In 293/OTR cells, OT stimulates inositol phosphate accumulation with an EC50 = 4.1 nM, an effect blocked by a potent and selective OT antagonist, L-366,948. Inositol Phosphates 32-50 oxytocin/neurophysin I prepropeptide Homo sapiens 18-20 3779039-0 1986 Oxytocin and vasopressin stimulate inositol phosphate production in human gestational myometrium and decidua cells. Inositol Phosphates 35-53 oxytocin/neurophysin I prepropeptide Homo sapiens 0-8 3779039-1 1986 The involvement of phosphoinositide hydrolysis in the action of oxytocin and vasopressin on the uterus was investigated in gestational myometrium and decidua cells by measuring the production of inositol phosphates. Inositol Phosphates 195-214 oxytocin/neurophysin I prepropeptide Homo sapiens 64-72