PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23347011-2 2013 An increase of [3H]-labeled inositol phosphate (IP1) formation by histamine (100 muM) or A23187 (100 nM) via the activation of phosphatidylinositol-specific phospholipase C (PI-PLC) to breakdown labeled substrate was observed, and this effect could be partially blocked by about half at 100 muM of 2-azafluorenones. Inositol Phosphates 28-46 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 48-51 22935142-8 2013 Likewise, apelin mediated a concentration-dependent depression in the maximal production of inositol phosphate (IP(1) ) and beta-arrestin recruitment to AT1 in response to Ang II. Inositol Phosphates 92-110 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 112-117 23589925-3 2013 Incubation of histamine caused increases in inositol phosphate (IP1) formation and intracellular free-calcium concentration [Ca2+]i in C6 glioma cells via the activation of a G-protein-coupled phospholipase C (PI-PLC). Inositol Phosphates 44-62 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 64-67 21705666-1 2011 The thyroid-stimulating hormone (TSH) receptor signals via G(s) to produce cAMP and via G(q/11) to produce inositol-1,4,5-trisphosphate, which is degraded to inositol monophosphate (IP1; phosphoinositide signaling). Inositol Phosphates 158-180 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 182-185 22646860-5 2011 Recently, a new homogeneous time-resolved fluorescence (HTRF) assay, detecting a downstream metabolite of IP3, inositol monophosphate (IP1), has overcome the drawbacks of the IP3 quantification, allowing its use in primary or secondary screening. Inositol Phosphates 111-133 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 135-138 1391326-11 1992 Treatment of ewes with PAF in vivo reduced inositol monophosphate (IP1) generated by oxytocin (10(-6) M) by 56.4%, compared to that in endometrium from vehicle-treated controls, and also inhibited the incorporation of 3H-inositol into glycerophosphoinositol (GPI). Inositol Phosphates 43-65 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 67-70 16965760-10 2006 Finally, the high assay specificity for D-myo-inositol 1 monophosphate (IP1(1)) opens new possibilities in developing selective assays to study the functional roles of the various isoforms of inositol phosphates. Inositol Phosphates 192-211 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 72-75 1333388-2 1992 The increase in inositol trisphosphate (IP3) was immediate and calcium independent while that of inositol monophosphate (IP1) was gradual and calcium dependent. Inositol Phosphates 97-119 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 121-124 2494076-4 1989 A marked decrease in inositol phosphate (IP1, IP2, IP3) formation in PMNLs of elderly was found under FMLP stimulation when compared to that of young subjects. Inositol Phosphates 21-39 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 41-44 1310020-3 1992 The dose-response curve for this suppression was very similar to that for stimulation of inositol monophosphate (IP1) formation and for stimulation of the initial rise of [Ca2+]i elicited by carbachol. Inositol Phosphates 89-111 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 113-116 1654212-3 1991 Formation of inositol phosphates (IP1, IP2, and IP3) in response to PAF was increased two- to threefold more than in vehicle control in U937 cells. Inositol Phosphates 13-32 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 34-37 1654212-3 1991 Formation of inositol phosphates (IP1, IP2, and IP3) in response to PAF was increased two- to threefold more than in vehicle control in U937 cells. Inositol Phosphates 13-32 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 39-42 2022708-6 1991 Involvement of PLC was assessed by inositol phosphate (IP1) turnover. Inositol Phosphates 35-53 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 55-58 1352896-6 1992 Following thrombin-induced platelet activation, there was rapid formation of 3H-labeled inositol phosphates (IPs) with inositol monophosphate (IP1) being the most abundant product. Inositol Phosphates 119-141 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 143-146 1827124-6 1991 However, significant increases in inositol monophosphate (IP1) and inositol biphosphate (IP2) were measured. Inositol Phosphates 34-56 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 58-61 2178105-4 1990 They respond between 0.1 and 1 mU/ml TSH for cyclic AMP accumulation and between 1 and 10 mU/ml TSH for inositol monophosphate (IP1) increase. Inositol Phosphates 104-126 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 128-131 2966739-5 1988 The CD3/CD4 heteroconjugate also shows significantly greater activity in stimulation of inositol phosphate IP1, IP2 and IP3 synthesis in T cells than the CD3 mAb alone, and again the activity is inhibited by free CD4 mAb. Inositol Phosphates 88-106 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 107-110 2784224-2 1989 When NK or LAK cells were conjugated to the sensitive target cells K562, an increased formation of both inositol monophosphate (IP1) and inositol trisphosphate (IP3) was detected. Inositol Phosphates 104-126 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 128-131 2995163-4 1985 Fractionation of [3H]inositol phosphates revealed that inositol triphosphate (IP3) and inositol diphosphate (IP2) increased earlier than inositol monophosphate (IP1). Inositol Phosphates 137-159 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 161-164 2820514-4 1987 The measurement of IP3 and its degradation products, inositol diphosphate (IP2) and inositol monophosphate (IP1) provides a way of assessing the extent to which this complex system has been activated. Inositol Phosphates 84-106 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Homo sapiens 108-111