PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9054374-11	1997	5-fold increases in IPs, respectively, when these cells co-expressed both the WT receptor and Galphaq.	Inositol Phosphates	20-23	G protein subunit alpha q	Homo sapiens	94-101	
11561099-9	2001	For example, when cells (WT PAFR + G(alpha)q) were exposed to WEB2086, SM10661, or alprazolam, the basal inositol phosphate production was reduced by 53 +/- 6, 44 +/- 3, and 54 +/- 4%, respectively.	Inositol Phosphates	105-123	G protein subunit alpha q	Homo sapiens	35-44	
10727532-2	2000	We used thyrotropin receptor, which is coupled to different G proteins, to investigate the regulation of Galphas- and Galphaq-mediated signaling (assessed by cAMP and inositol phosphate production, respectively).	Inositol Phosphates	167-185	G protein subunit alpha q	Homo sapiens	118-125	
8732687-4	1996	When cells were cotransfected with the cDNAs of receptor and different alpha-subunits of the Gq family (G alpha q, G alpha 11, G alpha 14, G alpha 15, and G alpha 16, a severalfold increase in the ligand-dependent inositol phosphate production could be observed, indicating that the receptors functionally interacted with all alpha-subunits of the G alpha q family.	Inositol Phosphates	214-232	G protein subunit alpha q	Homo sapiens	104-113	
32973514-8	2020	The BRET data corroborated with the data on the downstream Galphaq/inositol phosphate pathway.	Inositol Phosphates	67-85	G protein subunit alpha q	Homo sapiens	59-66	
18627427-6	2009	We also show that coupling of TSHR to G(alphaq) (as measured by inositolphosphate generation) is markedly reduced when the receptor is not cleaved.	Inositol Phosphates	64-81	G protein subunit alpha q	Homo sapiens	38-47	
7797501-1	1995	Activation of beta 2 adrenergic and muscarinic M2 receptors in cells expressing the receptors alone or together with G alpha q, G alpha 11, or G alpha 14 led to a very small stimulation of endogenous phospholipase C. However, when the receptors were coexpressed with G alpha 15 and G alpha 16, addition of appropriate ligands caused a severalfold increase in inositol phosphate production which was time- and dose-dependent.	Inositol Phosphates	359-377	G protein subunit alpha q	Homo sapiens	117-126	
20180987-6	2010	Pyk2 overexpression in HEK293 results in attenuated basal and agonist-stimulated inositol phosphate formation in mGluR1 expressing cells and involves a mechanism whereby Pyk2 displaces Galphaq/11 from the receptor.	Inositol Phosphates	81-99	G protein subunit alpha q	Homo sapiens	185-192	
18310092-6	2008	The Ca(2+) response was inhibited by Galphaq and phospholipase C (PLC) inhibitors as well as by intracellular Ca(2+) store depletion, indicating that it is mediated by a Gq-coupled receptor that activates the inositol phosphate (IP(3)) pathway consistent with the previously identified zinc-sensing receptor (ZnR).	Inositol Phosphates	209-227	G protein subunit alpha q	Homo sapiens	37-44	
16963356-4	2006	Angiotensin II stimulated accumulation of inositol phosphate and phosphorylation of MAP kinase was also observed, which indicated that the recombinant AT1aR could couple to endogenous Galphaq protein.	Inositol Phosphates	42-60	G protein subunit alpha q	Homo sapiens	184-191