PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35163345-9 2022 OGR1-dependent inositol phosphate (IP) production was significantly increased in CD14+ monocytes from IBD patients compared to healthy subjects. Inositol Phosphates 15-33 G protein-coupled receptor 68 Homo sapiens 0-4 35163345-9 2022 OGR1-dependent inositol phosphate (IP) production was significantly increased in CD14+ monocytes from IBD patients compared to healthy subjects. Inositol Phosphates 35-37 G protein-coupled receptor 68 Homo sapiens 0-4 31115941-1 2019 Ovarian cancer G-protein-coupled receptor 1 (OGR1), an acid-sensitive receptor, plays a key proton-sensing role through stimulation of inositol phosphate formation. Inositol Phosphates 135-153 G protein-coupled receptor 68 Homo sapiens 0-43 31115941-1 2019 Ovarian cancer G-protein-coupled receptor 1 (OGR1), an acid-sensitive receptor, plays a key proton-sensing role through stimulation of inositol phosphate formation. Inositol Phosphates 135-153 G protein-coupled receptor 68 Homo sapiens 45-49 16087674-1 2005 Ovarian cancer G-protein-coupled receptor 1 (OGR1) and GPR4 have recently been identified as proton-sensing or extracellular pH-responsive G-protein-coupled receptors stimulating inositol phosphate production and cAMP accumulation, respectively. Inositol Phosphates 179-197 G protein-coupled receptor 68 Homo sapiens 0-43 16087674-1 2005 Ovarian cancer G-protein-coupled receptor 1 (OGR1) and GPR4 have recently been identified as proton-sensing or extracellular pH-responsive G-protein-coupled receptors stimulating inositol phosphate production and cAMP accumulation, respectively. Inositol Phosphates 179-197 G protein-coupled receptor 68 Homo sapiens 45-49 16087674-4 2005 When small interfering RNAs (siRNAs) targeted for OGR1 and GPR4 were transfected to the cells, the acid-induced inositol phosphate production and [Ca(2+)](i) increase were markedly inhibited by the OGR1 siRNA but not by the GPR4 siRNA. Inositol Phosphates 112-130 G protein-coupled receptor 68 Homo sapiens 50-54 16087674-4 2005 When small interfering RNAs (siRNAs) targeted for OGR1 and GPR4 were transfected to the cells, the acid-induced inositol phosphate production and [Ca(2+)](i) increase were markedly inhibited by the OGR1 siRNA but not by the GPR4 siRNA. Inositol Phosphates 112-130 G protein-coupled receptor 68 Homo sapiens 198-202 12955148-3 2003 Here we show that ovarian cancer G-protein-coupled receptor 1 (OGR1), previously described as a receptor for sphingosylphosphorylcholine, acts as a proton-sensing receptor stimulating inositol phosphate formation. Inositol Phosphates 184-202 G protein-coupled receptor 68 Homo sapiens 18-61 12955148-3 2003 Here we show that ovarian cancer G-protein-coupled receptor 1 (OGR1), previously described as a receptor for sphingosylphosphorylcholine, acts as a proton-sensing receptor stimulating inositol phosphate formation. Inositol Phosphates 184-202 G protein-coupled receptor 68 Homo sapiens 63-67 12955148-7 2003 We detect expression of OGR1 in osteosarcoma cells and primary human osteoblast precursors, and show that these cells exhibit strong pH-dependent inositol phosphate formation. Inositol Phosphates 146-164 G protein-coupled receptor 68 Homo sapiens 24-28 26053506-6 2015 These OGR1 agonistic metals induce intracellular Gq-coupled inositol phosphate signals in OGR1-expressing cells and primary osteoclasts through OGR1. Inositol Phosphates 60-78 G protein-coupled receptor 68 Homo sapiens 6-10 26053506-6 2015 These OGR1 agonistic metals induce intracellular Gq-coupled inositol phosphate signals in OGR1-expressing cells and primary osteoclasts through OGR1. Inositol Phosphates 60-78 G protein-coupled receptor 68 Homo sapiens 90-94 26053506-6 2015 These OGR1 agonistic metals induce intracellular Gq-coupled inositol phosphate signals in OGR1-expressing cells and primary osteoclasts through OGR1. Inositol Phosphates 60-78 G protein-coupled receptor 68 Homo sapiens 90-94 16210776-0 2005 Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation. Inositol Phosphates 115-133 G protein-coupled receptor 68 Homo sapiens 55-98 16210776-0 2005 Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation. Inositol Phosphates 115-133 G protein-coupled receptor 68 Homo sapiens 100-104 16210776-1 2005 Ovarian cancer G-protein-coupled receptor 1 (OGR1), previously proposed as a receptor for sphingosylphosphorylcholine (SPC), has recently been identified as a proton-sensing or extracellular pH-responsive G-protein-coupled receptor stimulating inositol phosphate production, reflecting the activation of phospholipase C. In the present study, we found that acidic pH stimulated cAMP accumulation, reflecting the activation of adenylyl cyclase, in addition to inositol phosphate production in OGR1-expressing cells. Inositol Phosphates 244-262 G protein-coupled receptor 68 Homo sapiens 0-43 16210776-1 2005 Ovarian cancer G-protein-coupled receptor 1 (OGR1), previously proposed as a receptor for sphingosylphosphorylcholine (SPC), has recently been identified as a proton-sensing or extracellular pH-responsive G-protein-coupled receptor stimulating inositol phosphate production, reflecting the activation of phospholipase C. In the present study, we found that acidic pH stimulated cAMP accumulation, reflecting the activation of adenylyl cyclase, in addition to inositol phosphate production in OGR1-expressing cells. Inositol Phosphates 244-262 G protein-coupled receptor 68 Homo sapiens 45-49 16210776-1 2005 Ovarian cancer G-protein-coupled receptor 1 (OGR1), previously proposed as a receptor for sphingosylphosphorylcholine (SPC), has recently been identified as a proton-sensing or extracellular pH-responsive G-protein-coupled receptor stimulating inositol phosphate production, reflecting the activation of phospholipase C. In the present study, we found that acidic pH stimulated cAMP accumulation, reflecting the activation of adenylyl cyclase, in addition to inositol phosphate production in OGR1-expressing cells. Inositol Phosphates 244-262 G protein-coupled receptor 68 Homo sapiens 492-496 16210776-1 2005 Ovarian cancer G-protein-coupled receptor 1 (OGR1), previously proposed as a receptor for sphingosylphosphorylcholine (SPC), has recently been identified as a proton-sensing or extracellular pH-responsive G-protein-coupled receptor stimulating inositol phosphate production, reflecting the activation of phospholipase C. In the present study, we found that acidic pH stimulated cAMP accumulation, reflecting the activation of adenylyl cyclase, in addition to inositol phosphate production in OGR1-expressing cells. Inositol Phosphates 459-477 G protein-coupled receptor 68 Homo sapiens 0-43 16210776-1 2005 Ovarian cancer G-protein-coupled receptor 1 (OGR1), previously proposed as a receptor for sphingosylphosphorylcholine (SPC), has recently been identified as a proton-sensing or extracellular pH-responsive G-protein-coupled receptor stimulating inositol phosphate production, reflecting the activation of phospholipase C. In the present study, we found that acidic pH stimulated cAMP accumulation, reflecting the activation of adenylyl cyclase, in addition to inositol phosphate production in OGR1-expressing cells. Inositol Phosphates 459-477 G protein-coupled receptor 68 Homo sapiens 45-49 16210776-1 2005 Ovarian cancer G-protein-coupled receptor 1 (OGR1), previously proposed as a receptor for sphingosylphosphorylcholine (SPC), has recently been identified as a proton-sensing or extracellular pH-responsive G-protein-coupled receptor stimulating inositol phosphate production, reflecting the activation of phospholipase C. In the present study, we found that acidic pH stimulated cAMP accumulation, reflecting the activation of adenylyl cyclase, in addition to inositol phosphate production in OGR1-expressing cells. Inositol Phosphates 459-477 G protein-coupled receptor 68 Homo sapiens 492-496