PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8811660-5 1996 Using in situ hybridization and polymerase chain reaction, we show that in situ and in neurointermediate lobe explants, melanotropes express PACAP receptor type I isoforms that transduce through the cAMP and inositol phosphate pathways. Inositol Phosphates 208-226 adenylate cyclase activating polypeptide 1 Mus musculus 141-146 9523559-5 1998 Blockade of protein synthesis with cycloheximide, as well as inhibition by H89 of cyclic AMP-dependent protein kinase (but not by bisindolylmaleimide of protein kinase C) antagonized the influences exerted by PACAP on adenylyl cyclase activity and inositol phosphate formation. Inositol Phosphates 248-266 adenylate cyclase activating polypeptide 1 Mus musculus 209-214 9523559-8 1998 They demonstrate that prolonged exposure of CATH.a cells to PACAP results in the desensitization of the cyclic AMP pathway and superinduction of the inositol phosphate signal, through protein neosynthesis and cyclic AMP-dependent protein kinase activation. Inositol Phosphates 149-167 adenylate cyclase activating polypeptide 1 Mus musculus 60-65