PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9364473-4 1997 The P2Y1 receptor-selective antagonist PPADS completely blocked 2MeSATP-stimulated inositol phosphate accumulation, but only partially antagonized the response to ATP. Inositol Phosphates 83-101 purinergic receptor P2Y1 Homo sapiens 4-17 15193995-3 2004 PIT blocked 2-methylthio-ADP (2-MeSADP)-induced accumulation of inositol phosphates in 1321N1 astrocytoma cells stably expressing human P2Y(1) receptors in a non-competitive and concentration-dependent manner. Inositol Phosphates 64-83 purinergic receptor P2Y1 Homo sapiens 136-142 12181428-7 2002 Heterologous expression of the P2Y(1) and other P2Y receptors results in marked increases in basal inositol phosphate levels. Inositol Phosphates 99-117 purinergic receptor P2Y1 Homo sapiens 31-37 12181428-9 2002 Although marked elevation of inositol phosphate levels occurred with wild-type P2Y(1) receptor expression, levels in cells expressing the fusion protein were not different from those in wild-type CHO-K1 cells. Inositol Phosphates 29-47 purinergic receptor P2Y1 Homo sapiens 79-94 9401764-3 1997 As has been shown previously for the turkey and human P2Y1 receptors, the rat P2Y1 receptor expressed in either cell type responded to 2MeSATP with increases in inositol phosphate accumulation that were competitively blocked by the antagonist PPADS. Inositol Phosphates 161-179 purinergic receptor P2Y1 Homo sapiens 54-58 9401764-3 1997 As has been shown previously for the turkey and human P2Y1 receptors, the rat P2Y1 receptor expressed in either cell type responded to 2MeSATP with increases in inositol phosphate accumulation that were competitively blocked by the antagonist PPADS. Inositol Phosphates 161-179 purinergic receptor P2Y1 Homo sapiens 78-82 12634482-3 2003 When the cDNA was expressed in mammalian cells, the activation of P2Y(1) receptor by adenine nucleotides stimulated the accumulation of inositol phosphate, and adenosine 3",5"-bismonophosphate (A3P5P) or other antagonists blocked its action; these pharmacological properties showed resemblance of P2Y(1) receptor family in higher vertebrate. Inositol Phosphates 136-154 purinergic receptor P2Y1 Homo sapiens 66-81 10833413-2 2000 All these conjugates (AdoOC(O)Asp(n), n = 1-4) inhibited the 2MeSADP-stimulated synthesis of inositol phosphates in 1321N1 human astrocytoma cells stably expressing human P2Y(1) receptors. Inositol Phosphates 93-112 purinergic receptor P2Y1 Homo sapiens 171-177 8630005-5 1996 In COS-7 cells transfected with the coding sequence inserted into the pcDNA3 expression vector, 2-methylthioATP and ATP produced a strong stimulation of inositol phosphates, a typical response of a P2Y1 receptor. Inositol Phosphates 153-172 purinergic receptor P2Y1 Homo sapiens 198-211