PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9218782-8 1997 It is likely that these mutations inactivate the Btk pathway in cell signalling by reducing its affinity for inositol phosphates, which causes a failure in translocation of the kinase to the cell membrane. Inositol Phosphates 109-128 Bruton tyrosine kinase Homo sapiens 49-52 9240435-2 1997 In this paper, we describe the inositol phosphate binding specificity of the Btk PH domain and different inositol polyphosphate binding properties among the PH domains of Tec family kinases. Inositol Phosphates 31-49 Bruton tyrosine kinase Homo sapiens 77-80