PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10953540-7	2000	In addition, Cu(2+)-deficient rats exhibited a decrease (153.5 +/- 30.9%) in the magnitude of CCK-8-stimulated total inositol phosphate formation compared with control rats (220.8 +/- 11.9%).	Inositol Phosphates	117-135	cholecystokinin	Rattus norvegicus	94-97	
11451139-8	2001	However, CCK-induced inositol phosphate formation was not changed by 10(-9) M octreotide.	Inositol Phosphates	21-39	cholecystokinin	Rattus norvegicus	9-12	
9359417-5	1997	The CCK-8 dose response for causing changes in the cytosolic calcium concentration ([Ca2+]i) was similar to that for p125(FAK) and paxillin phosphorylation, and both were to the left of that for receptor occupation and inositol phosphate production.	Inositol Phosphates	219-237	cholecystokinin	Rattus norvegicus	4-7	
7538685-3	1995	CCK and carbachol induced sizeable increases in inositol phosphates while growth factors did not.	Inositol Phosphates	48-67	cholecystokinin	Rattus norvegicus	0-3	
8735845-6	1996	Interestingly, when tested for their capacity to influence inositol phosphate formation, induced by CCK8 in CHO cells transfected with the rat CCK-B receptor, compound 13 behaved as a full CCK-B antagonist with an IC50 value of 18 +/- 1 nM, being as potent as the antagonist L-365,260 and PD-134,308 (IC50 values respectively, 39 +/- 17 and 30 +/- 2 nM), whereas compound 16 was found to behave as a partial CCK-B agonist.	Inositol Phosphates	59-77	cholecystokinin	Rattus norvegicus	100-103	
2841557-4	1988	CCK (50 nmol/L) alone increases phosphoinositide (PI) hydrolysis in islets, an event reflected by an increase in 3H efflux from myo[2-3H]inositol prelabeled islets and parallel accumulations of labeled inositol phosphates.	Inositol Phosphates	202-221	cholecystokinin	Rattus norvegicus	0-3	
2043103-5	1991	Both mastoparan and CCK induced turnover of inositol phosphates, at concentrations higher than necessary to induce oscillations.	Inositol Phosphates	44-63	cholecystokinin	Rattus norvegicus	20-23	
2553506-1	1989	We have recently shown that F- can mimic the actions of cholecystokinin (CCK) on amylase release, Ca2+ mobilization and inositol phosphate generation in pancreatic acinar cells.	Inositol Phosphates	120-138	cholecystokinin	Rattus norvegicus	56-71	
2553506-1	1989	We have recently shown that F- can mimic the actions of cholecystokinin (CCK) on amylase release, Ca2+ mobilization and inositol phosphate generation in pancreatic acinar cells.	Inositol Phosphates	120-138	cholecystokinin	Rattus norvegicus	73-76	
2461094-8	1988	Furthermore, the effects of submaximal CCK concentrations on inositol phosphate accumulation in membranes were markedly potentiated in the presence of 100 microM GTP, which alone was ineffective.	Inositol Phosphates	61-79	cholecystokinin	Rattus norvegicus	39-42	
15502636-6	2004	RESULTS: CCK-8-induced IP formation at all concentrations used was significantly reduced in diabetic acini, though IP formation was increased in a concentration-dependent manner.	Inositol Phosphates	23-25	cholecystokinin	Rattus norvegicus	9-12