PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28351683-5 2017 Acid hydrolysis of both compounds yielded oleanolic acid (3) which was non or least toxic to human peripheral blood mono nuclear cells (Selectivity index = >10) while retaining similar macrofilaricidal (IC50 = 38.4 muM) and microfilaricidal (IC50 = 35.6 muM) activities. Oleanolic Acid 42-56 latexin Homo sapiens 218-221 28351683-5 2017 Acid hydrolysis of both compounds yielded oleanolic acid (3) which was non or least toxic to human peripheral blood mono nuclear cells (Selectivity index = >10) while retaining similar macrofilaricidal (IC50 = 38.4 muM) and microfilaricidal (IC50 = 35.6 muM) activities. Oleanolic Acid 42-56 latexin Homo sapiens 257-260 28351683-6 2017 In adult female worms treated with 50 and 100 muM doses of oleanolic acid, condensation of nuclear DNA, apoptotic body formation and tissue damage was observed by using Hoechst 33342 staining, TUNEL assay and Hematoxylin and Eosin staining respectively. Oleanolic Acid 59-73 latexin Homo sapiens 46-49 26750249-4 2016 Good results were determined for oleanolic acid derived 7 for tumor cell lines 518A2 (melanoma, EC50=3.3 muM), A2780 (ovarian carcinoma, EC50=3.4 muM) and HT29 (colon adenocarcinoma, EC50=5.6 muM) while being significantly less cytotoxic for fibroblasts (EC50=20.4 muM). Oleanolic Acid 33-47 latexin Homo sapiens 105-108 26750249-4 2016 Good results were determined for oleanolic acid derived 7 for tumor cell lines 518A2 (melanoma, EC50=3.3 muM), A2780 (ovarian carcinoma, EC50=3.4 muM) and HT29 (colon adenocarcinoma, EC50=5.6 muM) while being significantly less cytotoxic for fibroblasts (EC50=20.4 muM). Oleanolic Acid 33-47 latexin Homo sapiens 146-149 26750249-4 2016 Good results were determined for oleanolic acid derived 7 for tumor cell lines 518A2 (melanoma, EC50=3.3 muM), A2780 (ovarian carcinoma, EC50=3.4 muM) and HT29 (colon adenocarcinoma, EC50=5.6 muM) while being significantly less cytotoxic for fibroblasts (EC50=20.4 muM). Oleanolic Acid 33-47 latexin Homo sapiens 146-149 26750249-4 2016 Good results were determined for oleanolic acid derived 7 for tumor cell lines 518A2 (melanoma, EC50=3.3 muM), A2780 (ovarian carcinoma, EC50=3.4 muM) and HT29 (colon adenocarcinoma, EC50=5.6 muM) while being significantly less cytotoxic for fibroblasts (EC50=20.4 muM). Oleanolic Acid 33-47 latexin Homo sapiens 146-149 26253631-4 2015 Oleanolic acid, a positive control, inhibited PTP1B activity at 0.7 muM (IC50). Oleanolic Acid 0-14 latexin Homo sapiens 68-71 22799301-7 2012 The IC50 values achieved for maslinic acid, staurosporine, H-7, sphingosine, rottlerin, ursolic acid and oleanolic acid were 11.52, 0.011, 0.767, 2.45, 5.46, 27.93 and 39.29 muM, respectively. Oleanolic Acid 105-119 latexin Homo sapiens 174-177 21561086-6 2011 Oleanolic acid (1) also inhibited the cellular metabolism by AKR1B10 (IC(50), 4 muM) and decreased mitomycin C tolerance of colon cancer HT29 cells. Oleanolic Acid 0-14 latexin Homo sapiens 80-83