PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18778688-2 2008 Here we identified a new oleanolic acid derivative, 3-beta-(2-carboxybenzoyloxy)-oleanolic acid (NPLC441), which functioned as a competitive PTP1B inhibitor and enhanced insulin-stimulated phosphorylation of IR and AKT in HepG2 cells. Oleanolic Acid 25-39 insulin Homo sapiens 170-177 26843885-0 2015 Oleanolic Acid Attenuates Insulin Resistance via NF-kappaB to Regulate the IRS1-GLUT4 Pathway in HepG2 Cells. Oleanolic Acid 0-14 insulin Homo sapiens 26-33 26843885-1 2015 The aim of our study is to elucidate the mechanisms of oleanolic acid (OA) on insulin resistance (IR) in HepG2 cells. Oleanolic Acid 55-69 insulin Homo sapiens 78-85 26843885-1 2015 The aim of our study is to elucidate the mechanisms of oleanolic acid (OA) on insulin resistance (IR) in HepG2 cells. Oleanolic Acid 71-73 insulin Homo sapiens 78-85 23531458-1 2013 Twenty-four sugar-substituted oleanolic acid derivatives (1a-1f, 2a-2j, and 3a-3h) were synthesized in a concise and efficient strategy and their effects on the inhibition of protein tyrosine phosphatase 1B (PTP1B) and insulin-sensitizing response were evaluated in vitro. Oleanolic Acid 30-44 insulin Homo sapiens 219-226 23531458-4 2013 Structure-activity relationship study of these sugar-substituted oleanolic acid derivatives demonstrated that PTP1B inhibitory activity and insulin-sensitizing response were strongly influenced by both the carbohydrate moiety at the C-3 position and the long acidic chain at C-28 position of oleanolic acid. Oleanolic Acid 65-79 insulin Homo sapiens 140-147