PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32028542-0 2020 Oleanolic acid mitigates interleukin-1beta-induced chondrocyte dysfunction by regulating miR-148-3p-modulated FGF2 expression. Oleanolic Acid 0-14 fibroblast growth factor 2 Homo sapiens 110-114 32028542-2 2020 The present study is aimed to investigate the molecular mechanisms underlying in oleanolic acid (OLA)-prevented interleukin-1beta (IL-1beta)-induced chondrocyte dysfunction via the miR-148-3p/FGF2 signaling pathway. Oleanolic Acid 81-95 fibroblast growth factor 2 Homo sapiens 192-196 32028542-2 2020 The present study is aimed to investigate the molecular mechanisms underlying in oleanolic acid (OLA)-prevented interleukin-1beta (IL-1beta)-induced chondrocyte dysfunction via the miR-148-3p/FGF2 signaling pathway. Oleanolic Acid 97-100 fibroblast growth factor 2 Homo sapiens 192-196 32028542-8 2020 Additionally, FGF2 protein expression levels elevated by IL-1beta were down-regulated by OLA and miR-148-3p mimics transfection. Oleanolic Acid 89-92 fibroblast growth factor 2 Homo sapiens 14-18 32028542-12 2020 CONCLUSIONS: Our present findings expounded a protective effect of OLA on IL-1beta-induced chondrocyte dysfunction, and a novel signal cascade the miR-148-3p/FGF2 signaling pathway might be a potential therapeutic target of OLA to prevent the progression of osteoarthritis (OA). Oleanolic Acid 224-227 fibroblast growth factor 2 Homo sapiens 158-162