PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31742469-2	2020	In our previous work, a synthetic oleanolic acid (OA) derivative C10a with PTP1B inhibitory activity has been reported.	Oleanolic Acid	50-52	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	75-80	
31742469-2	2020	In our previous work, a synthetic oleanolic acid (OA) derivative C10a with PTP1B inhibitory activity has been reported.	Oleanolic Acid	34-48	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	75-80	
23531458-0	2013	Synthesis and biological evaluation of oleanolic acid derivatives as PTP1B inhibitors.	Oleanolic Acid	39-53	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	69-74	
31743023-10	2019	Cya-3-Ara could also be regarded as a synergistic inhibitor (CI <= 0.54) of oleanolic acid to obtain a better inhibitory effect on PTP1B.	Oleanolic Acid	79-93	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	134-139	
27373628-7	2016	Oleanolic acid, a positive control, inhibited PTP1B activity at 0.7+-0.1 microM (IC50) in the same experiment.	Oleanolic Acid	0-14	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	46-51	
24721313-0	2014	Synthesis and evaluation of several oleanolic acid glycoconjugates as protein tyrosine phosphatase 1B inhibitors.	Oleanolic Acid	36-50	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	70-101	
24721313-1	2014	Sixteen novel oleanolic acid triterpenoid saponins were synthesized in an efficient and practical strategy, and their inhibitory activities against protein tyrosine phosphatase 1B (PTP1B) and selectivity over T-cell protein tyrosine phosphatase (TCPTP) were evaluated in vitro.	Oleanolic Acid	14-28	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	148-179	
24721313-1	2014	Sixteen novel oleanolic acid triterpenoid saponins were synthesized in an efficient and practical strategy, and their inhibitory activities against protein tyrosine phosphatase 1B (PTP1B) and selectivity over T-cell protein tyrosine phosphatase (TCPTP) were evaluated in vitro.	Oleanolic Acid	14-28	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	181-186	
26253631-4	2015	Oleanolic acid, a positive control, inhibited PTP1B activity at 0.7 muM (IC50).	Oleanolic Acid	0-14	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	46-51	
25264584-0	2014	Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition.	Oleanolic Acid	13-27	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	85-91	
25264584-2	2014	Pentacyclic acid triterpenes such as oleanolic acid (OA) have proved to be excellent PTP-1B inhibitors, thus, the purpose of current work was to generate a series of derivatives that improve the pharmacological effect of OA.	Oleanolic Acid	37-51	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	85-91	
25264584-2	2014	Pentacyclic acid triterpenes such as oleanolic acid (OA) have proved to be excellent PTP-1B inhibitors, thus, the purpose of current work was to generate a series of derivatives that improve the pharmacological effect of OA.	Oleanolic Acid	53-55	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	85-91	
23531458-1	2013	Twenty-four sugar-substituted oleanolic acid derivatives (1a-1f, 2a-2j, and 3a-3h) were synthesized in a concise and efficient strategy and their effects on the inhibition of protein tyrosine phosphatase 1B (PTP1B) and insulin-sensitizing response were evaluated in vitro.	Oleanolic Acid	30-44	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	175-206	
23531458-1	2013	Twenty-four sugar-substituted oleanolic acid derivatives (1a-1f, 2a-2j, and 3a-3h) were synthesized in a concise and efficient strategy and their effects on the inhibition of protein tyrosine phosphatase 1B (PTP1B) and insulin-sensitizing response were evaluated in vitro.	Oleanolic Acid	30-44	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	208-213	
23531458-4	2013	Structure-activity relationship study of these sugar-substituted oleanolic acid derivatives demonstrated that PTP1B inhibitory activity and insulin-sensitizing response were strongly influenced by both the carbohydrate moiety at the C-3 position and the long acidic chain at C-28 position of oleanolic acid.	Oleanolic Acid	65-79	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	110-115	
23531458-4	2013	Structure-activity relationship study of these sugar-substituted oleanolic acid derivatives demonstrated that PTP1B inhibitory activity and insulin-sensitizing response were strongly influenced by both the carbohydrate moiety at the C-3 position and the long acidic chain at C-28 position of oleanolic acid.	Oleanolic Acid	292-306	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	110-115	
20964318-0	2010	Synthesis and biological evaluation of oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B.	Oleanolic Acid	39-53	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	83-114	
20964318-2	2010	Derivatives of oleanolic acid were synthesized and evaluated as PTP1B inhibitors.	Oleanolic Acid	15-29	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	64-69	
18778688-2	2008	Here we identified a new oleanolic acid derivative, 3-beta-(2-carboxybenzoyloxy)-oleanolic acid (NPLC441), which functioned as a competitive PTP1B inhibitor and enhanced insulin-stimulated phosphorylation of IR and AKT in HepG2 cells.	Oleanolic Acid	25-39	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	141-146