PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31888388-0 2021 Design and synthesis of VEGFR-2 inhibitors based on oleanolic acid moiety. Oleanolic Acid 52-66 kinase insert domain receptor Homo sapiens 24-31 35369968-0 2022 Design and semisynthesis of oleanolic acid derivatives as VEGF inhibitors: Inhibition of VEGF-induced proliferation, angiogenesis, and VEGFR2 activation in HUVECs. Oleanolic Acid 28-42 kinase insert domain receptor Homo sapiens 135-141 35369968-2 2022 Recent studies have revealed that oleanolic acid (OA), a natural pentacyclic triterpenoid, inhibited the VEGF/VEGFR2 signaling pathway and angiogenesis in HUVECs, which may represent an attractive VEGF inhibitor. Oleanolic Acid 34-48 kinase insert domain receptor Homo sapiens 110-116 31888388-1 2021 In this study, twenty-four oleanolic acid (OA) derivatives were rationally designed based on molecule docking studies and their VEGFR-2 inhibitory activities were tested by Homogeneous time-resolved fluorescence (HTRF) method in vitro. Oleanolic Acid 27-41 kinase insert domain receptor Homo sapiens 128-135 31888388-1 2021 In this study, twenty-four oleanolic acid (OA) derivatives were rationally designed based on molecule docking studies and their VEGFR-2 inhibitory activities were tested by Homogeneous time-resolved fluorescence (HTRF) method in vitro. Oleanolic Acid 43-45 kinase insert domain receptor Homo sapiens 128-135 31888388-4 2021 The results indicated that insertion of phenylurea group with a linker at position C-28 of OA can increase the activity against VEGFR-2 significantly. Oleanolic Acid 91-93 kinase insert domain receptor Homo sapiens 128-135 29065844-0 2018 Oleanolic Acid Inhibits Colorectal Cancer Angiogenesis by Blocking the VEGFR2 Signaling Pathway. Oleanolic Acid 0-14 kinase insert domain receptor Homo sapiens 71-77