PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34035231-8	2021	Consistently, AKR1B10 overexpression induced cancer cell aggressiveness, whereas suppression of AKR1B10 by siRNA or its small molecular inhibitor, oleanolic acid, reversed the CBX7 deficiency-induced cellular effects.	Oleanolic Acid	147-161	aldo-keto reductase family 1 member B10	Homo sapiens	96-103	
21561086-4	2011	Among them, oleanolic acid (1) was found to be the most potent competitive inhibitor (inhibition constant, 72 nM) with the highest AKR1B10/AKR1B1 selectivity ratio of 1370.	Oleanolic Acid	12-26	aldo-keto reductase family 1 member B10	Homo sapiens	131-138	
25304374-6	2014	Inhibition of AKR1B10 by oleanolic acid (OA) showed a dose-dependent inhibition of cell growth with IC50 at 30 microM.	Oleanolic Acid	25-39	aldo-keto reductase family 1 member B10	Homo sapiens	14-21	
27417252-7	2016	Intriguingly, overexpression of AKR1B10 in the cells resulted in a decrease in PPARgamma expression, which was recovered by addition of an AKR1B10 inhibitor oleanolic acid, inferring that PPARgamma is a downstream target of AKR1B10-dependent mechanism underlying the CDDP resistance.	Oleanolic Acid	157-171	aldo-keto reductase family 1 member B10	Homo sapiens	32-39	
27417252-7	2016	Intriguingly, overexpression of AKR1B10 in the cells resulted in a decrease in PPARgamma expression, which was recovered by addition of an AKR1B10 inhibitor oleanolic acid, inferring that PPARgamma is a downstream target of AKR1B10-dependent mechanism underlying the CDDP resistance.	Oleanolic Acid	157-171	aldo-keto reductase family 1 member B10	Homo sapiens	139-146	
27417252-7	2016	Intriguingly, overexpression of AKR1B10 in the cells resulted in a decrease in PPARgamma expression, which was recovered by addition of an AKR1B10 inhibitor oleanolic acid, inferring that PPARgamma is a downstream target of AKR1B10-dependent mechanism underlying the CDDP resistance.	Oleanolic Acid	157-171	aldo-keto reductase family 1 member B10	Homo sapiens	139-146	
21561086-6	2011	Oleanolic acid (1) also inhibited the cellular metabolism by AKR1B10 (IC(50), 4 muM) and decreased mitomycin C tolerance of colon cancer HT29 cells.	Oleanolic Acid	0-14	aldo-keto reductase family 1 member B10	Homo sapiens	61-68