PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7864640-3	1995	Under these conditions IL-1-stimulated proteoglycan degradation was inhibited by bafilomycin A1 with an IC50 of < 10 nM in both chondrocyte monolayers and articular cartilage explants.	bafilomycin A1	81-95	interleukin 1 alpha	Homo sapiens	23-27	
7864640-8	1995	IL-1 also stimulated the synthesis and secretion of prostromelysin by chondrocyte monolayers, however, under conditions in which IL-1 stimulated proteoglycan release was totally blocked by bafilomycin A1, there was no effect on IL-1-stimulated stromelysin secretion or stromelysin enzyme activity.	bafilomycin A1	189-203	interleukin 1 alpha	Homo sapiens	0-4	
7864640-8	1995	IL-1 also stimulated the synthesis and secretion of prostromelysin by chondrocyte monolayers, however, under conditions in which IL-1 stimulated proteoglycan release was totally blocked by bafilomycin A1, there was no effect on IL-1-stimulated stromelysin secretion or stromelysin enzyme activity.	bafilomycin A1	189-203	interleukin 1 alpha	Homo sapiens	129-133	
7864640-8	1995	IL-1 also stimulated the synthesis and secretion of prostromelysin by chondrocyte monolayers, however, under conditions in which IL-1 stimulated proteoglycan release was totally blocked by bafilomycin A1, there was no effect on IL-1-stimulated stromelysin secretion or stromelysin enzyme activity.	bafilomycin A1	189-203	interleukin 1 alpha	Homo sapiens	129-133	
34425162-4	2021	Pretreatment of HNE cells with the specific vacuolar H+-ATPase inhibitor bafilomycin A1 reduced the RV-C03 RNA levels in the ASL; inflammatory cytokines, including interleukin (IL)-1beta, IL-6 and IL-8, in the supernatant; the mRNA expression of the RV-C receptor cadherin-related family member 3 (CDHR3) in the cells; and the number of acidic endosomes where RV-B RNA enters the cytoplasm.	bafilomycin A1	73-87	interleukin 1 alpha	Homo sapiens	164-186	
35092164-7	2022	While blocking the fusion of autophagosomes with lysosomes by bafilomycin A1(BafA1), the reduced NLRP3 inflammasome activity induced by RAPA was significantly restored, with increased protein levels of NLRP3 and cleaved Casp-1(p10), as well as IL-1beta secretion.	bafilomycin A1	62-76	interleukin 1 alpha	Homo sapiens	244-252	
34062977-6	2021	Using our existing protocol, inflammasome activation was induced in IL-1alpha-primed ARPE-19 cells with the proteasome and autophagy inhibitors MG-132 and bafilomycin A1, respectively.	bafilomycin A1	155-169	interleukin 1 alpha	Homo sapiens	68-77