PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34048091-5 2021 Pre-incubation of retina with bafilomycin A1 (an inhibitor of neurotransmitter uptake into synaptic vesicles) abolished NMDAR-mediated noise in AII, but not A17 amacrines, suggesting a vesicular source of glutamate activates AII NMDARs, whereas a non-vesicular source activates A17 NMDARs. bafilomycin A1 30-44 NLR family pyrin domain containing 3 Homo sapiens 144-147 35092164-7 2022 While blocking the fusion of autophagosomes with lysosomes by bafilomycin A1(BafA1), the reduced NLRP3 inflammasome activity induced by RAPA was significantly restored, with increased protein levels of NLRP3 and cleaved Casp-1(p10), as well as IL-1beta secretion. bafilomycin A1 62-76 NLR family pyrin domain containing 3 Homo sapiens 97-102 35092164-7 2022 While blocking the fusion of autophagosomes with lysosomes by bafilomycin A1(BafA1), the reduced NLRP3 inflammasome activity induced by RAPA was significantly restored, with increased protein levels of NLRP3 and cleaved Casp-1(p10), as well as IL-1beta secretion. bafilomycin A1 62-76 NLR family pyrin domain containing 3 Homo sapiens 202-207 34048091-5 2021 Pre-incubation of retina with bafilomycin A1 (an inhibitor of neurotransmitter uptake into synaptic vesicles) abolished NMDAR-mediated noise in AII, but not A17 amacrines, suggesting a vesicular source of glutamate activates AII NMDARs, whereas a non-vesicular source activates A17 NMDARs. bafilomycin A1 30-44 NLR family pyrin domain containing 3 Homo sapiens 225-228 29486589-10 2019 Moreover, blocking autophagy with bafilomycin A1 or LC3B siRNA resulted in oxidant accumulation, NLRP3 inflammasome hyperactivation, and collagen deposition. bafilomycin A1 34-48 NLR family pyrin domain containing 3 Homo sapiens 97-102 33145969-0 2021 Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification. bafilomycin A1 0-14 NLR family pyrin domain containing 3 Homo sapiens 24-29 33145969-3 2021 Here we report that pharmacological inhibition of V-ATPase with bafilomycin A1 exacerbated LPS-induced NLRP3 inflammasome activation in primary human monocytes. bafilomycin A1 64-78 NLR family pyrin domain containing 3 Homo sapiens 103-108 30138927-6 2018 METHODS: NLRP3 inflammasomes were activated in human RPE cells by blocking proteasomes and autophagy using MG-132 and bafilomycin A1 (BafA), respectively. bafilomycin A1 134-138 NLR family pyrin domain containing 3 Homo sapiens 9-14