PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34925701-6 2021 Furthermore, EX-527 (a specific inhibitor of SIRT1) exposure counteracted the protective effect of VB 12 by promoting oxidative stress and aggravating mitochondrial damage without influencing CBS, indicating that vitamin B12 regulates SIRT1 to improve pancreatical damage by activating CBS. 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide 13-19 cystathionine beta-synthase Homo sapiens 286-289