PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26616666-8 2015 At clinically relevant concentrations, verapamil blocked hCav1.2 and hERG, as did vanoxerine and bepridil both of which also blocked hNav1.5. Bepridil 97-105 sodium voltage-gated channel alpha subunit 5 Homo sapiens 133-140 20625312-0 2010 Efficacy of low-dose bepridil for prevention of ventricular fibrillation in patients with Brugada syndrome with and without SCN5A mutation. Bepridil 21-29 sodium voltage-gated channel alpha subunit 5 Homo sapiens 124-129 20625312-3 2010 Among 130 patients with Brugada-type electrocardiogram (ECG), low-dose bepridil was administered to seven patients because of repetitive VF episodes, including three with and four without SCN5A mutation. Bepridil 71-79 sodium voltage-gated channel alpha subunit 5 Homo sapiens 188-193 20625312-5 2010 Frequencies of VF episodes were reduced after treatment with low-dose bepridil in all three patients with the SCN5A mutation (before: 0.33 versus after: 0.02 episodes/month, P < 0.01), but not in all four patients without the SCN5A mutation (before: 0.43 versus after: 2.94 episodes/month, P = nonsignificant). Bepridil 70-78 sodium voltage-gated channel alpha subunit 5 Homo sapiens 110-115 20625312-5 2010 Frequencies of VF episodes were reduced after treatment with low-dose bepridil in all three patients with the SCN5A mutation (before: 0.33 versus after: 0.02 episodes/month, P < 0.01), but not in all four patients without the SCN5A mutation (before: 0.43 versus after: 2.94 episodes/month, P = nonsignificant). Bepridil 70-78 sodium voltage-gated channel alpha subunit 5 Homo sapiens 229-234 20625312-7 2010 Treatment with bepridil prevented recurrence of VF along with improvement of ST elevation and LAS40 in patients with Brugada syndrome with the SCN5A mutation. Bepridil 15-23 sodium voltage-gated channel alpha subunit 5 Homo sapiens 143-148