PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26436896-8	2016	Both quetiapine and norquetiapine were agonists at 5-HT1A receptors, and the anxiolytic-like activity of norquetiapine in rat punished responding was blocked by the 5-HT1A antagonist, WAY100635.	Quetiapine Fumarate	5-15	5-hydroxytryptamine receptor 1A	Rattus norvegicus	51-57	
31601072-0	2019	The therapeutic effect of quetiapine on cognitive impairment associated with 5-HT1A presynaptic receptor involved schizophrenia.	Quetiapine Fumarate	26-36	5-hydroxytryptamine receptor 1A	Rattus norvegicus	77-83	
26436896-8	2016	Both quetiapine and norquetiapine were agonists at 5-HT1A receptors, and the anxiolytic-like activity of norquetiapine in rat punished responding was blocked by the 5-HT1A antagonist, WAY100635.	Quetiapine Fumarate	5-15	5-hydroxytryptamine receptor 1A	Rattus norvegicus	165-171	
23049514-9	2012	One possible explanation for these negative findings could be that the intrinsic 5HT(1A) agonist activity of quetiapine on its own is of such significance that it is not further enhanced by buspirone.	Quetiapine Fumarate	109-119	5-hydroxytryptamine receptor 1A	Rattus norvegicus	81-87	
12445705-4	2002	The present study determined whether quetiapine, iloperidone and melperone, 5-HT(2A)/D(2) antagonist atypical APDs, also increase cortical DA and ACh release, and whether these effects are related to 5-HT(1A) agonism.	Quetiapine Fumarate	37-47	5-hydroxytryptamine receptor 1A	Rattus norvegicus	200-207	
12445705-9	2002	These results indicate that quetiapine, iloperidone and melperone preferentially increase DA release in the mPFC, compared to the NAC via a 5-HT(1A)-related mechanism.	Quetiapine Fumarate	28-38	5-hydroxytryptamine receptor 1A	Rattus norvegicus	140-147	
12445705-10	2002	However, 5-HT(1A) agonism may be important only for quetiapine-induced ACh release.	Quetiapine Fumarate	52-62	5-hydroxytryptamine receptor 1A	Rattus norvegicus	9-16	
11277607-9	2001	However, the clinical relevance may be clarified by the atypical antipsychotic drugs clozapine, quetiapine and ziprasidone which combine D2 receptor antagonism and 5-HT1A agonism.	Quetiapine Fumarate	96-106	5-hydroxytryptamine receptor 1A	Rattus norvegicus	164-170