PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16713676-0 2006 Effects of quetiapine on the brain-derived neurotrophic factor expression in the hippocampus and neocortex of rats. Quetiapine Fumarate 11-21 brain-derived neurotrophic factor Rattus norvegicus 29-62 26176197-0 2015 Quetiapine and repetitive transcranial magnetic stimulation ameliorate depression-like behaviors and up-regulate the proliferation of hippocampal-derived neural stem cells in a rat model of depression: The involvement of the BDNF/ERK signal pathway. Quetiapine Fumarate 0-10 brain-derived neurotrophic factor Rattus norvegicus 225-229 17442489-4 2007 Chronic administration of drugs used to treat SZ and BD, such as lithium, valproate, quetiapine, clozapine, and olanzapine, increases BDNF expression in rat brain. Quetiapine Fumarate 85-95 brain-derived neurotrophic factor Rattus norvegicus 134-138 16713676-2 2006 This study aimed to investigate the effects of chronic quetiapine administration on the BDNF mRNA expression in hippocampus and neocortex of rats with or without immobilization stress. Quetiapine Fumarate 55-65 brain-derived neurotrophic factor Rattus norvegicus 88-92 16713676-3 2006 The chronic administration (21 days) of quetiapine (10 mg/kg) significantly attenuated the decreased BDNF mRNA expression in the both hippocampal and cortical regions of rats caused by immobilization stress, and significantly increased the BDNF mRNA expression in the dentate gyrus of rats even without the immobilization stress. Quetiapine Fumarate 40-50 brain-derived neurotrophic factor Rattus norvegicus 101-105 16713676-3 2006 The chronic administration (21 days) of quetiapine (10 mg/kg) significantly attenuated the decreased BDNF mRNA expression in the both hippocampal and cortical regions of rats caused by immobilization stress, and significantly increased the BDNF mRNA expression in the dentate gyrus of rats even without the immobilization stress. Quetiapine Fumarate 40-50 brain-derived neurotrophic factor Rattus norvegicus 240-244 16713676-4 2006 These results could add some theoretical bases to explain why quetiapine may improve cognitive symptoms of schizophrenia by stimulating BDNF mRNA expression. Quetiapine Fumarate 62-72 brain-derived neurotrophic factor Rattus norvegicus 136-140 16271709-2 2005 Our previous study has shown that chronic administration of quetiapine attenuates the decrease in levels of brain-derived neurotrophic factor (BDNF) in the hippocampi of rats subjected to chronic-restraint stress. Quetiapine Fumarate 60-70 brain-derived neurotrophic factor Rattus norvegicus 108-141 16652337-0 2006 Synergetic effects of quetiapine and venlafaxine in preventing the chronic restraint stress-induced decrease in cell proliferation and BDNF expression in rat hippocampus. Quetiapine Fumarate 22-32 brain-derived neurotrophic factor Rattus norvegicus 135-139 16271709-2 2005 Our previous study has shown that chronic administration of quetiapine attenuates the decrease in levels of brain-derived neurotrophic factor (BDNF) in the hippocampi of rats subjected to chronic-restraint stress. Quetiapine Fumarate 60-70 brain-derived neurotrophic factor Rattus norvegicus 143-147 32702397-0 2020 Oral quetiapine treatment results in time-dependent alterations of recognition memory and brain-derived neurotrophic factor-related signaling molecules in the hippocampus of rats. Quetiapine Fumarate 5-15 brain-derived neurotrophic factor Rattus norvegicus 90-123 15486491-0 2004 Quetiapine regulates FGF-2 and BDNF expression in the hippocampus of animals treated with MK-801. Quetiapine Fumarate 0-10 brain-derived neurotrophic factor Rattus norvegicus 31-35 15486491-2 2004 Administration of the atypical antipsychotic quetiapine resulted in a marked elevation of FGF-2 and BDNF mRNA levels in the rat hippocampus, but only under conditions of reduced NMDA receptor activity. Quetiapine Fumarate 45-55 brain-derived neurotrophic factor Rattus norvegicus 100-104 11872258-0 2002 Quetiapine attenuates the immobilization stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus. Quetiapine Fumarate 0-10 brain-derived neurotrophic factor Rattus norvegicus 68-101 11872258-2 2002 This study examined the influence of quetiapine on the decrease of brain-derived neurotrophic factor (BDNF) expression, induced by chronic immobilization stress, in the hippocampus of the rat. Quetiapine Fumarate 37-47 brain-derived neurotrophic factor Rattus norvegicus 67-100 11872258-2 2002 This study examined the influence of quetiapine on the decrease of brain-derived neurotrophic factor (BDNF) expression, induced by chronic immobilization stress, in the hippocampus of the rat. Quetiapine Fumarate 37-47 brain-derived neurotrophic factor Rattus norvegicus 102-106 11872258-3 2002 Pretreatment with 10 mg/kg of quetiapine markedly attenuated the stress-induced decrease in levels of BDNF protein, as determined by Western blot analyses, and the reduction of BDNF immunoreactivity, in hippocampal pyramidal and dentate granular neurons. Quetiapine Fumarate 30-40 brain-derived neurotrophic factor Rattus norvegicus 102-106 11872258-3 2002 Pretreatment with 10 mg/kg of quetiapine markedly attenuated the stress-induced decrease in levels of BDNF protein, as determined by Western blot analyses, and the reduction of BDNF immunoreactivity, in hippocampal pyramidal and dentate granular neurons. Quetiapine Fumarate 30-40 brain-derived neurotrophic factor Rattus norvegicus 177-181 32702397-4 2020 The purpose of the studies described here was to evaluate one of the most commonly prescribed APDs, quetiapine, for chronic effects on recognition memory, brain-derived neurotrophic factor (BDNF), its precursor proBDNF, as well as relevant downstream signaling molecules that are known to influence neuronal plasticity and cognition. Quetiapine Fumarate 100-110 brain-derived neurotrophic factor Rattus norvegicus 155-188 32702397-6 2020 The results indicated that oral quetiapine at a dose that did not induce catalepsy, led to time-dependent impairments in NOR performance, increases in the proBDNF/BDNF ratio, and decreases in Akt and CREB phosphorylation in the hippocampus. Quetiapine Fumarate 32-42 brain-derived neurotrophic factor Rattus norvegicus 158-162