PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19577630-5 2010 To explore the mechanism of LPS-induced IDO expression, microglia were pretreated with the c-Jun-N-terminal kinase (JNK) inhibitor SP600125 for 30 min before LPS treatment. pyrazolanthrone 131-139 indoleamine 2,3-dioxygenase 1 Mus musculus 40-43 19577630-6 2010 We found that SP600125 blocked JNK phosphorylation and significantly decreased IDO expression induced by LPS, which was accompanied by a reduction of LPS-induced expression of TNFalpha and IL-6. pyrazolanthrone 14-22 indoleamine 2,3-dioxygenase 1 Mus musculus 79-82 17367785-6 2007 However, LPS-induced expression of IDO was inhibited by LY294002 and SP600125 but not by JAK inhibitor I, SB203580, or U0126. pyrazolanthrone 69-77 indoleamine 2,3-dioxygenase 1 Mus musculus 35-38