PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25572464-12	2014	With bevacizumab and SP600125 treatment, the level of VEGF-A and AP-1 decreased while bcl-2 increased.	pyrazolanthrone	21-29	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	65-69	
29385629-8	2018	After blocking AP-1 with SP600125, we detected TBG and the Th17 related cytokines (IL-6 and IL-17).	pyrazolanthrone	25-33	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	15-19	
23404530-6	2013	In addition, the NF-kappaB inhibitor, pyrrolidine dithiocarbamate (PDTC), and the AP-1 inhibitor, SP600125, decreased the protein levels of FN, collagen I and PAI-1, suggesting a role for the NF-kappaB and AP-1 pathways in the regulation of ECM accumulation induced by HG in RPMCs.	pyrazolanthrone	98-106	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	82-86	
23404530-6	2013	In addition, the NF-kappaB inhibitor, pyrrolidine dithiocarbamate (PDTC), and the AP-1 inhibitor, SP600125, decreased the protein levels of FN, collagen I and PAI-1, suggesting a role for the NF-kappaB and AP-1 pathways in the regulation of ECM accumulation induced by HG in RPMCs.	pyrazolanthrone	98-106	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	206-210	
21046201-0	2011	Enteral arginine modulates inhibition of AP-1/c-Jun by SP600125 in the postischemic gut.	pyrazolanthrone	55-63	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	41-45	
22212430-10	2012	Thrombin (0.3-3.0 U/mL) increased activator protein-1 (AP-1)-luciferase activity, which was inhibited by the JNK inhibitor SP600125.	pyrazolanthrone	123-131	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	34-53	
22212430-10	2012	Thrombin (0.3-3.0 U/mL) increased activator protein-1 (AP-1)-luciferase activity, which was inhibited by the JNK inhibitor SP600125.	pyrazolanthrone	123-131	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	55-59	
21046201-8	2011	In conclusion, SP600125 attenuated the activity of c-Jun/AP-1, iNOS expression, and neutrophil infiltration induced by arginine following mesenteric I/R.	pyrazolanthrone	15-23	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	57-61	
17615156-5	2007	Prolongation of events associated with NF-kappaB activation was also observed in cells pretreated and/or cotransfected with the JNK inhibitor SP600125 or deletion mutants of MEKK1 (MEKK1-KD) or Jun (Jun-DN).	pyrazolanthrone	142-150	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	199-205	
16531007-11	2006	Electrophoretic mobility shift assays performed showed a maximal upregulation of AP1 binding activity after 60 min of H2O2 treatment, which was significantly inhibited by SP600125 and H89.	pyrazolanthrone	171-179	Jun proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	81-84