PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26903805-3	2016	In this study, we used the small molecule JNK inhibitor SP600125 to examine the effect of JNK signaling abrogation on the development of hair cells in the zebrafish lateral line neuromast.	pyrazolanthrone	56-64	mitogen-activated protein kinase 8b	Danio rerio	42-45	
27438150-0	2016	Effect of JNK inhibitor SP600125 on hair cell regeneration in zebrafish (Danio rerio) larvae.	pyrazolanthrone	24-32	mitogen-activated protein kinase 8b	Danio rerio	10-13	
27438150-4	2016	We eliminated hair cells of 5-day post-fertilization zebrafish larvae using neomycin followed by JNK inhibition with SP600125.	pyrazolanthrone	117-125	mitogen-activated protein kinase 8b	Danio rerio	97-100	
27438150-8	2016	Finally, JNK inhibition with SP600125 decreased the expression of genes related to Wnt.	pyrazolanthrone	29-37	mitogen-activated protein kinase 8b	Danio rerio	9-12	
24349481-9	2013	Inhibition of Jnk, a downstream target of Wnt/PCP signaling (via morpholino antisense knockdown and pharmacological inhibition with the kinase inhibitor SP600125) phenocopied pCAME-treated embryos.	pyrazolanthrone	153-161	mitogen-activated protein kinase 8b	Danio rerio	14-17	
23261760-5	2013	TGF-beta1 enhanced glioma-induced angiogenesis, which was inhibited by JNK inhibitor SP600125 but not p38 MAPK inhibitor SB202190, ERK inhibitor PD98059, or PI3K inhibitor LY294002, indicating the important role of TGF-beta1 and JNK pathways in this process.	pyrazolanthrone	85-93	mitogen-activated protein kinase 8b	Danio rerio	71-74	
23884438-6	2013	SP600125, a JNK-specific inhibitor, gives rise to high mortality in zebrafish, similar to that caused by the jnk1 RNA interference.	pyrazolanthrone	0-8	mitogen-activated protein kinase 8b	Danio rerio	12-15	
23884438-8	2013	The results also indicate that the inhibition of JNK by SP600125 suppresses the ovarian differentiation during the embryo development in zebrafish.	pyrazolanthrone	56-64	mitogen-activated protein kinase 8b	Danio rerio	49-52	
23261760-5	2013	TGF-beta1 enhanced glioma-induced angiogenesis, which was inhibited by JNK inhibitor SP600125 but not p38 MAPK inhibitor SB202190, ERK inhibitor PD98059, or PI3K inhibitor LY294002, indicating the important role of TGF-beta1 and JNK pathways in this process.	pyrazolanthrone	85-93	mitogen-activated protein kinase 8b	Danio rerio	229-232	
21751222-0	2013	Exposure to the JNK inhibitor SP600125 (anthrapyrazolone) during early zebrafish development results in morphological defects.	pyrazolanthrone	30-38	mitogen-activated protein kinase 8b	Danio rerio	16-19	
21751222-1	2013	SP600125 (anthrapyrazolone) is a synthetic polyaromatic chemical that inhibits c-Jun N-terminal kinase (JNK) signaling by interfering with phosphorylation of c-Jun.	pyrazolanthrone	0-8	mitogen-activated protein kinase 8b	Danio rerio	79-102	
21751222-1	2013	SP600125 (anthrapyrazolone) is a synthetic polyaromatic chemical that inhibits c-Jun N-terminal kinase (JNK) signaling by interfering with phosphorylation of c-Jun.	pyrazolanthrone	0-8	mitogen-activated protein kinase 8b	Danio rerio	104-107