PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25994505-8	2015	In addition, addition of SP600125 or SB203580 also blocked apigenin-induced ALP activity, OPN, Runx2, and OSX expression and meanwhile inhibited bone nodule formation.	pyrazolanthrone	25-33	secreted phosphoprotein 1	Homo sapiens	90-93	
28052093-4	2017	Our results showed that JNK inhibition by the specific inhibitor SP600125 or adenovirus expressing small interfering RNA (siRNA) targeting JNK (AdR-si-JNK) significantly decreased BMP9-induced gene and protein expression of early and late osteogenic markers, such as runt-related transcription factor 2 (Runx2), alkaline phosphatase (ALP), osteopontin (OPN), and osteocalcin (OCN), in hPDLSCs.	pyrazolanthrone	65-73	secreted phosphoprotein 1	Homo sapiens	340-351	
28052093-4	2017	Our results showed that JNK inhibition by the specific inhibitor SP600125 or adenovirus expressing small interfering RNA (siRNA) targeting JNK (AdR-si-JNK) significantly decreased BMP9-induced gene and protein expression of early and late osteogenic markers, such as runt-related transcription factor 2 (Runx2), alkaline phosphatase (ALP), osteopontin (OPN), and osteocalcin (OCN), in hPDLSCs.	pyrazolanthrone	65-73	secreted phosphoprotein 1	Homo sapiens	353-356	
27959394-6	2017	The use of JNK inhibitor (SP600125) enhanced the inhibitory effects of miR-214 overexpression on osteogenic differentiation, ALP activity, and Col I, OCN and OPN gene expression in the BMSCs.	pyrazolanthrone	26-34	secreted phosphoprotein 1	Homo sapiens	158-161	
31362241-8	2019	VSMCs treated with siRNA-ANXA3 or SP600125 showed decreased expression of JNK, caspase-3, osteopontin (OPN), Bax, and matrix metalloproteinase-9 (MMP-9), as well as phosphate (p)-JNK, but increased the expression of alpha smooth muscle actin (alpha-SMA), beta-tubulin, and Bcl-2.	pyrazolanthrone	34-42	secreted phosphoprotein 1	Homo sapiens	90-101	
31362241-8	2019	VSMCs treated with siRNA-ANXA3 or SP600125 showed decreased expression of JNK, caspase-3, osteopontin (OPN), Bax, and matrix metalloproteinase-9 (MMP-9), as well as phosphate (p)-JNK, but increased the expression of alpha smooth muscle actin (alpha-SMA), beta-tubulin, and Bcl-2.	pyrazolanthrone	34-42	secreted phosphoprotein 1	Homo sapiens	103-106	
24239640-11	2014	The elevated SPP1 expression was inhibited by SP600125 or SB203580.	pyrazolanthrone	46-54	secreted phosphoprotein 1	Homo sapiens	13-17