PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30171832-6	2019	The IL-22-induced down-regulation of Cx43 expression and decrease in GJIC can be significantly blocked by the JNK inhibitor SP600125 and by the overexpression of IL-22RA2 (which specifically binds to IL-22 and inhibits its activity), but not by the NF-kappaB inhibitor BAY11-7082, in HaCaT cells.	pyrazolanthrone	124-132	gap junction protein alpha 1	Homo sapiens	37-41	
17367753-6	2007	In agreement, AML1-ETO overexpression in leukemic U937 cells activated c-Jun N-terminal kinase (JNK), while its specific inhibitor SP600125 effectively abrogated AML1-ETO-induced Cx43 expression, indicating that JNK signaling pathway contributes to AML1-ETO induced Cx43 expression.	pyrazolanthrone	131-139	gap junction protein alpha 1	Homo sapiens	179-183	
17367753-6	2007	In agreement, AML1-ETO overexpression in leukemic U937 cells activated c-Jun N-terminal kinase (JNK), while its specific inhibitor SP600125 effectively abrogated AML1-ETO-induced Cx43 expression, indicating that JNK signaling pathway contributes to AML1-ETO induced Cx43 expression.	pyrazolanthrone	131-139	gap junction protein alpha 1	Homo sapiens	266-270	
24002703-7	2013	JSH-23 (30 muM), an NF-kB inhibitor, and SP600125 (10 muM), an AP-1/c-Jun inhibitor, attenuated the loss of Cx43.	pyrazolanthrone	41-49	gap junction protein alpha 1	Homo sapiens	108-112