PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30171832-6 2019 The IL-22-induced down-regulation of Cx43 expression and decrease in GJIC can be significantly blocked by the JNK inhibitor SP600125 and by the overexpression of IL-22RA2 (which specifically binds to IL-22 and inhibits its activity), but not by the NF-kappaB inhibitor BAY11-7082, in HaCaT cells. pyrazolanthrone 124-132 interleukin 22 Homo sapiens 4-9