PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20920558-11	2010	Furthermore, PDTC/Cu complex could trigger the expressions of ER stress-associated signaling molecules including Grp78, Grp94, caspase-12, ATF4, and CHOP, which could be reversed by SP600125.	pyrazolanthrone	182-190	activating transcription factor 4	Homo sapiens	139-143	
19059405-0	2009	SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression.	pyrazolanthrone	0-8	activating transcription factor 4	Homo sapiens	68-72	
19059405-4	2009	Overexpression of ATF4 upregulated the expression of Redd1, while suppression of ATF4 expression by siRNA enhanced the level of S6 phosphorylation by downregulating the SP600125-induced increase in Redd1 expression.	pyrazolanthrone	169-177	activating transcription factor 4	Homo sapiens	18-22	
19059405-4	2009	Overexpression of ATF4 upregulated the expression of Redd1, while suppression of ATF4 expression by siRNA enhanced the level of S6 phosphorylation by downregulating the SP600125-induced increase in Redd1 expression.	pyrazolanthrone	169-177	activating transcription factor 4	Homo sapiens	81-85	
19059405-5	2009	Together, these results indicate that SP600125 inhibits mTOR activity via an ATF4-induced increase in Redd1 expression.	pyrazolanthrone	38-46	activating transcription factor 4	Homo sapiens	77-81