PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26879145-9 2016 Recombinant human BMP-9-induced ALP activity was suppressed by SB203580, SP600125, and U0126, which are inhibitors of p38, c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase 1/2 (ERK1/2), respectively. pyrazolanthrone 73-81 growth differentiation factor 2 Homo sapiens 18-23 23977991-4 2013 BMP9-induced osteogenic differentiation of MSCs was dramatically inhibited by JNKs inhibitor SP600125. pyrazolanthrone 93-101 growth differentiation factor 2 Homo sapiens 0-4 23977991-5 2013 Moreover, BMP9-activated Smads signaling was decreased by SP600125 treatment in MSCs. pyrazolanthrone 58-66 growth differentiation factor 2 Homo sapiens 10-14 28052093-4 2017 Our results showed that JNK inhibition by the specific inhibitor SP600125 or adenovirus expressing small interfering RNA (siRNA) targeting JNK (AdR-si-JNK) significantly decreased BMP9-induced gene and protein expression of early and late osteogenic markers, such as runt-related transcription factor 2 (Runx2), alkaline phosphatase (ALP), osteopontin (OPN), and osteocalcin (OCN), in hPDLSCs. pyrazolanthrone 65-73 growth differentiation factor 2 Homo sapiens 180-184