PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33692840-11	2021	The upregulation of Nrf2, MRP1 and of Nrf2, and MRP1 mRNA expression levels in CSE-stimulated cells was inhibited by pretreatment with SP600125 (a JNK pathway inhibitor).	pyrazolanthrone	135-143	NFE2 like bZIP transcription factor 2	Homo sapiens	38-42	
35624854-9	2022	SB203580 (a p38 MAPK inhibitor) and SP600125 (a JNK inhibitor) attenuated the tomentosin-induced phosphorylation of Nrf2, suggesting that JNK and p38 MAPK signaling pathways can contribute to the tomentosin-induced Nrf2 activation through phosphorylation of Nrf2.	pyrazolanthrone	36-44	NFE2 like bZIP transcription factor 2	Homo sapiens	116-120	
35624854-9	2022	SB203580 (a p38 MAPK inhibitor) and SP600125 (a JNK inhibitor) attenuated the tomentosin-induced phosphorylation of Nrf2, suggesting that JNK and p38 MAPK signaling pathways can contribute to the tomentosin-induced Nrf2 activation through phosphorylation of Nrf2.	pyrazolanthrone	36-44	NFE2 like bZIP transcription factor 2	Homo sapiens	215-219	
35624854-9	2022	SB203580 (a p38 MAPK inhibitor) and SP600125 (a JNK inhibitor) attenuated the tomentosin-induced phosphorylation of Nrf2, suggesting that JNK and p38 MAPK signaling pathways can contribute to the tomentosin-induced Nrf2 activation through phosphorylation of Nrf2.	pyrazolanthrone	36-44	NFE2 like bZIP transcription factor 2	Homo sapiens	258-262	
33692840-11	2021	The upregulation of Nrf2, MRP1 and of Nrf2, and MRP1 mRNA expression levels in CSE-stimulated cells was inhibited by pretreatment with SP600125 (a JNK pathway inhibitor).	pyrazolanthrone	135-143	NFE2 like bZIP transcription factor 2	Homo sapiens	20-24	
33426091-15	2020	Proliferation and invasion of RA-FLS incubated with TNF-alpha and nrf2 siRNA were inhibited by pretreatment with JNK inhibitor SP600125.	pyrazolanthrone	127-135	NFE2 like bZIP transcription factor 2	Homo sapiens	66-70	
32104530-9	2020	We confirmed this phenomenon by the suppressed nuclear Nrf2 activation in cells that were treated with respective inhibitors (PD98059, SP600125, and GF109203X).	pyrazolanthrone	135-143	NFE2 like bZIP transcription factor 2	Homo sapiens	55-59	
27912883-9	2016	However, miltirone-induced Nrf2/HO-1 expression can only be effectively blocked by JNK inhibitor SP600125.	pyrazolanthrone	97-105	NFE2 like bZIP transcription factor 2	Homo sapiens	27-31	
31351365-7	2019	Indeed, the results of our experiments using LY294002 and SP600125 indicated that NG may stimulate Nrf2 through PI3K/Akt and JNK pathway activation.	pyrazolanthrone	58-66	NFE2 like bZIP transcription factor 2	Homo sapiens	99-103	
21241747-5	2011	Nrf2 knockdown by siRNA and the inhibition of JNK (c-Jun N-terminal kinase) by SP600125 decreased both CA-induced NGF expression and Nrf2 nuclear accumulation and suppressed their synergistic effect on NGF expression.	pyrazolanthrone	79-87	NFE2 like bZIP transcription factor 2	Homo sapiens	133-137