PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21826704-11 2011 Chemical inhibition of JNK1/2 (SP600125) in MPD cells increased IGF-I expression (non-significantly), however, did not enhance differentiation. pyrazolanthrone 31-39 insulin-like growth factor 1 Mus musculus 64-69 19937471-3 2009 Inhibition of the MAPK pathway with SB203580, PD98059, or SP600125 significantly decreased IGF-I-induced AR phosphorylation and total AR protein expression. pyrazolanthrone 58-66 insulin-like growth factor 1 Mus musculus 91-96 19937471-4 2009 IGF-I-induced nuclear fraction of total AR and phosphorylated AR were significantly inhibited by SB203580, PD98059, or SP600125. pyrazolanthrone 119-127 insulin-like growth factor 1 Mus musculus 0-5 19937471-6 2009 Confocal images showed that IGF-I-induced AR nuclear translocation from cytosol was significantly blocked by SB203580, PD98059, or SP600125, suggesting that the MAPK pathway regulates IGF-I-induced AR nuclear localization in skeletal muscle cells. pyrazolanthrone 131-139 insulin-like growth factor 1 Mus musculus 28-33 19937471-6 2009 Confocal images showed that IGF-I-induced AR nuclear translocation from cytosol was significantly blocked by SB203580, PD98059, or SP600125, suggesting that the MAPK pathway regulates IGF-I-induced AR nuclear localization in skeletal muscle cells. pyrazolanthrone 131-139 insulin-like growth factor 1 Mus musculus 184-189 14963047-8 2004 A role for JNK in the survival of FL5.12 cells was supported by the observation that the JNK inhibitor SP600125 suppressed IGF-I-mediated protection from apoptosis. pyrazolanthrone 103-111 insulin-like growth factor 1 Mus musculus 123-128