PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22706709-2	2013	Herein, we examine the effect of the JNK specific inhibitor, SP600125, on the level of functional proteins or transcription factors related to endoplasmic reticulum (ER) and oxidative stress induced by amyloid beta (Abeta).	pyrazolanthrone	61-69	amyloid beta precursor protein	Rattus norvegicus	216-221	
26899864-9	2016	Compare to Abeta-only group, the administration of SP600125 and/or bucladesine improved spatial reference learning (P < 0.001) and memory (P < 0.01).	pyrazolanthrone	51-59	amyloid beta precursor protein	Rattus norvegicus	11-16	
26899864-10	2016	Compared to the Abeta-only group, the treatment with SP600125 and/or bucladesine also reduced beclin1, Atg7, Atg12, and LC3 II/I (P < 0.0001) which was similar to amount of normal rats.	pyrazolanthrone	53-61	amyloid beta precursor protein	Rattus norvegicus	16-21	
26899864-11	2016	In summary, it seems that the improvement of spatial memory by SP600125 and/or bucladesine in Abeta-injected rats is in relation with normalizing of autophagy to the physiologic level, possibly through neuroprotection and/or neuroplasticity.	pyrazolanthrone	63-71	amyloid beta precursor protein	Rattus norvegicus	94-99	
22706709-9	2013	Also, we observed that pretreatment with SP600125 leads to a greater increase of nuclear related factor-2 (Nrf2) level compared with the Abeta-injected group.	pyrazolanthrone	41-49	amyloid beta precursor protein	Rattus norvegicus	137-142