PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20556404-4	2010	The role of the MAP kinases in TGF-beta1-dependent induction of the 37/67 LR was examined by addition of PD98059, SB202190 and SP600125.	pyrazolanthrone	127-135	transforming growth factor, beta 1	Mus musculus	31-40	
33236148-10	2021	Subsequently, it was shown that the ERK inhibitor, PD98059, and JNK inhibitor, SP600125, were able to reverse TGF-beta1-induced autophagy and fibrosis.	pyrazolanthrone	79-87	transforming growth factor, beta 1	Mus musculus	110-119	
25203596-8	2015	And the expression of arginase-1 and TGF-beta1 was partially blocked by the pretreated ERK biochemical inhibitor (U0126) instead of the JNK inhibitor (SP600125) and p38MAPK inhibitor (SB203580).	pyrazolanthrone	151-159	transforming growth factor, beta 1	Mus musculus	37-46	
25095732-10	2014	alpha2AP-induced the TGF-beta production was significantly reduced by SP600125, c-Jun N-terminal kinase (JNK) specific inhibitor.	pyrazolanthrone	70-78	transforming growth factor, beta 1	Mus musculus	21-29	
20112290-9	2010	The JNK inhibitor SP600125 blocked high glucose-induced FN expression and inhibited cell cycle regulatory protein expression induced by high glucose or TGF-beta(1).	pyrazolanthrone	18-26	transforming growth factor, beta 1	Mus musculus	152-163	
19127219-5	2009	Treatment with SP600125 stimulated Smad2 phosphorylation and enhanced TGF-beta1-induced Smad2 phosphorylation.	pyrazolanthrone	15-23	transforming growth factor, beta 1	Mus musculus	70-79	
15824967-5	2005	SP600125 suppressed TGF-beta-induced SAPK/JNK phosphorylation.	pyrazolanthrone	0-8	transforming growth factor, beta 1	Mus musculus	20-28	
18407296-6	2008	SP600125, a specific inhibitor of stress-activated protein kinase (SAPK)/c-Jun N-terminal kinase (JNK), markedly reduced the HSP27 expression induced by TGF-beta.	pyrazolanthrone	0-8	transforming growth factor, beta 1	Mus musculus	153-161	
15824967-4	2005	SP600125, a specific inhibitor of SAPK/JNK, markedly reduced TGF-beta-induced VEGF synthesis.	pyrazolanthrone	0-8	transforming growth factor, beta 1	Mus musculus	61-69	
15824967-7	2005	A combination of SP600125 and PD98059 or SP600125 and SB203580 suppressed TGF-beta-stimulated VEGF synthesis in an additive manner.	pyrazolanthrone	17-25	transforming growth factor, beta 1	Mus musculus	74-82	
15824967-7	2005	A combination of SP600125 and PD98059 or SP600125 and SB203580 suppressed TGF-beta-stimulated VEGF synthesis in an additive manner.	pyrazolanthrone	41-49	transforming growth factor, beta 1	Mus musculus	74-82